Journal of Biochemistry and Molecular Biology (한국생화학회지)

Korean Society for Biochemistry and Molecular Biology (생화학분자생물학회)
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Studies on the Antioxidant Components of Korean Ginseng [I]

인삼의 항산화활성 성분에 관한 연구 [I]

  • Han, Byung-Hoon (Natural Products Research Institute, Seoul National University) ;
  • Park, Myung-Hwan (Natural Products Research Institute, Seoul National University) ;
  • Woo, Lin-Keun (Natural Products Research Institute, Seoul National University) ;
  • Woo, Won-Sick (Natural Products Research Institute, Seoul National University) ;
  • Han, Yong-Nam (Natural Products Research Institute, Seoul National University)
  • Received : 1979.02.28
  • Published : 1979.03.30

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Abstract

This paper is concerned with the studies on the effective components possessing antioxidant activity, with a view to demonstrate the anti-aging activity of Korean ginseng. Feeding the extract of Korean ginseng or its effective component to mice inhibited strongly the lipid peroxidation induced by ethanol intoxication. From the extract of Korean red ginseng, one effective component, Compound A, mp. $143^{\circ}$, $C_6H_6O_3$, was isolated by chromatographic purification and its chemical structure was determined as 3-hydroxy-2-methyl-$\gamma$-pyrone (maltol).

한국인삼의 노화방지 효과를 입증하는 의도에서 인삼의 항산화활성을 다루었다. 인삼 또는 그 유효성분을 추출하여 마우스에 투여하면 알코홀 투여로 인하여 상승되는 지질 과산화물의 함량을 감소시켜주었으며 그 유효성분의 화학구조를 결정한 결과 3-hydroxy-2-methyl-$\gamma$-Pyrone (maltol)임을 밝혔다.

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