Korean Journal of Pharmacognosy (생약학회지)
- Volume 23 Issue 4
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- Pages.240-247
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- 1992
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- 0253-3073(pISSN)
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- 2288-9299(eISSN)
Isolation and Antimicrobial Activity of a Naphthoquinone from Impatiens balsamina
봉선화의 항균활성성분(抗菌活性成分)과 항균력(抗菌力)에 관(關)한 연구(硏究)
- Kang, Soo-Chul (College of Pharmacy, Chosun University) ;
- Moon, Young-Hee (College of Pharmacy, Chosun University)
- Published : 1992.12.30
Abstract
Impatiens balsamina Linne(Balsaminaceae) known as 'BONG SUN HWA' in Korea and has been used for the treatment of scrofulosis, carbunculus and dysenteria etc. Bioassay-guided fractionation of MeOH extract from the whole plants of Impatiens balsamina has afforded a simple naphthoquinone derivative, 2-methoxy-1,4-naphthoquinone. The structure of this compound was established by spectroscopic methods. This compound possessed strong antifungal activity against Candida albicans, AspergiIlus niger, Crytococcus neoformans and Epidermophyton floccusum. The activity of 2-methoxy-1,4-naphthoquinone on E. floccusum
Keywords
- Impatiens balsamina;
- Balsaminaceae;
- 2-methoxy-1;
- 4-naphthoquinone;
- antibacterial;
- antifungal activity