Microbiology and Biotechnology Letters (한국미생물·생명공학회지)

The Korean Society for Microbiology and Biotechnology (한국미생물·생명공학회)
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Studies on the Optimization of Media Composition and Cultural Conditions for Kasugamycin Production, by Streptomyces kasugaensis

Streptomyces kasugaensis의 Kasugamycin 생산배지조성 및 배양조건의 검토

  • 오영준 (동신대학교 식품영양학과)
  • Published : 1992.10.01
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Abstract

This study was conducted in order to optimize the media composition and cultural conditions for kasugamycin production by Streptomyces kasugaensis. The optimum culture conditions are pH 6.6 (before sterilization) and $28^{\circ}C$ for the production of kasugamycin. The kasugamycin concentration was not increased when silicone oil as antifoam agent was added. The addition of water during the cultivation in the various media showed a positive effect for the production of kasugamycin.

본 연구는 농용항생제인 kasugamycin의 생산을 위하여 S.kasugaensis의 배양조건 및 배지조성을 고찰하였다. Kasugamycin 발효시 최적 탄소원 및 질소원은 각각 soybean oil과 soybean flour였다. 배지 최적온도는 28'C, 최적 pH는 6.6이었다. 본 배양의 최적 접종 상태는 64-68시간 배양한 전배양액으로 접종하였으며, 발효중 물의 첨가는 생산성의 증가를 나타냈으나 소포제로서 silicone coil 첨가는 별 영향을 관찰할 수가 없었다.

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References

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