The Korean Journal of Food And Nutrition (한국식품영양학회지)
- Volume 5 Issue 1
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- Pages.7-12
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- 1992
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- 1225-4339(pISSN)
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- 2287-4992(eISSN)
Inhibitory Activity of Acidic Polysaccharides of Korean Red Ginseng on Lipolytic Action of Toxohormone-L from Cancerous Ascites Fluid
홍삼 산성 다당체 성분의 암독소 호르몬-L에 의한 지방 분해 저해 활성
Abstract
This study was devised to observe the inhibitory effect of 7 kinds PG(PG1, PG2, PG3, PG4, PG5, PG6 and PG7) and of 5 kinds PG4(PG41, PG42, PG43, PG44 and PG45) of the acidic polysaccharide fraction from Korean red ginseng on a lipolytic action of Toxohormone-L. Toxohormone-L is a lipolytic factor, found in ascites fluid. of sarcoma-180 bearing mice and of patients with hepatoma. A substance that inhibited the lipolytic action of toxohormone-L was isolated from red ginseng powder. This substance was an acidic polysaccharides In vitro test showed that the inhibitory effect of PG4 and PG43 fraction of the lipolysis by Toxohormone-L was highest percent among other treatments at concentration of 50, 100, 200, 500 and 1,000ug/ml of reaction mixture. And total inhibitory activity(units) of PG1 and PG4, and PG4 s was highest among other treatments at the same concentration.
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