Korean Journal of Pharmacognosy (생약학회지)

The Korean Society of Pharmacognosy (한국생약학회)
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The Antigastritic Effect of Taraxaci Herba

포공영의 항위염 작용

  • Lee, Eun-Bang (Natural Products Research Institute, Seoul National University) ;
  • Kim, Jung-Keun (Natural Products Research Institute, Seoul National University) ;
  • Kim, Ok-Kyung (College of Natural Science, Seoul Woman's University)
  • 이은방 (서울대학교 천연물과학연구소) ;
  • 김정근 (서울대학교 천연물과학연구소) ;
  • 김옥경 (서울여자대학교 자연과학대학)
  • Published : 1993.12.30
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Abstract

The methanol extract of Taraxaci Herba was found to have inhibitory effect on the gastric lesion induced by HCl-ethanol. The systematic fractionation of the methanol extract resulted in positive action with water fraction in the gastric lesion. It also showed significant inhibition of gastric lesion induced by HCl-aspirin and absolute ethanol, but did not prevent indomethacin induced gastric lesion. This fraction did not affect basal gastric acid secretion but showed a decrease of pepsin activity in pylorus-ligated rats.

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