Journal of Food Hygiene and Safety (한국식품위생안전성학회지)

The Korean Society of Food Hygiene and Safety (한국식품위생안전성학회)
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Antimutagenicity of Small Water Dropwort Juice on the Microbial Mutagencity Induced by 2-Aminofluorene

2-AF에 의해 유발된 미생물 변이원성에 미치는 들미나리즙의 돌연변이 억제작용

  • 한규석 (강원도 보건환경연구원) ;
  • 정의호 (강원도 보건환경연구원) ;
  • 함승시 (강원대학교 식품공학과) ;
  • 심태흠 (강원도 보건환경연구원) ;
  • 이택수 (강원도 보건환경연구원) ;
  • 이해금 (강원도 보건환경연구원)
  • Published : 1993.12.01
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Abstract

This study was conducted to examine the stages showing the antimutagenic effects on the microbial mutation by addition of the juice extracted from small water dropwort. It was not able to find out the signal showing the genic derepression or change of gene repair system by addition of the juice. And it was hardly possible to expect the conversion of 2-AF to inactive form by the juice. however the longer 2-AF and S-9 mix were contacted before addition of the juice, the stronger the microbial mutagenisity of 2-AF was, and after addition of the juice, the mutagenicity was decreased rapidly. It seems that some components in the juice act as inhibitor of a enzyme in S-9 mix, and block the conversion of 2-AF to the ultimate mutagen.

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