A Study of a Biodegradale Inorganic-Organic Composite Artificial Bone Substitute -Part 1. Synthesis of an Apatite with Similar Crystallinity to Bone-

  • Choon Ki Lee (Department of Orthopaedic Surgery, College of Medicine, Seoul National University) ;
  • Hwal Suh (Institute of Biomedical Engineering, College of Medicine, Seoul National University)
  • Published : 1994.06.01

Abstract

To develop an artificial bone substitute that is gradually degraded and replaced by the regenerated natural bone, the authors designed a composite that consists consisted of calcium phosphate and collagen according to the natural bone's main composition. The crystallinity of the synthesized apatite was shown to depend on the synthesis temperature. Carbonate apatite synthesized at $58{\circ}C$ demonstrated crystallinity very similar to that of the natural bone. By sintering the apatite over $700{\circ}C$ in vacuum, porous carbonate apatite could be obtained, and the pore extent was controllable according to the additive hydrogenperoxide volume.

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References

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