Korean Journal of Pharmacognosy (생약학회지)

The Korean Society of Pharmacognosy (한국생약학회)
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Chemical Constituents and Biological Activity of Kalopanacis Cortex

해동피의 화학성분 및 생리활성

  • Lee, Eun (College of Life Science & Natural Resources, Sangji University) ;
  • Choi, Moo-Young (College of Natural Science & Engineering Sangji University) ;
  • Park, Hee-Juhn (College of Life Science & Natural Resources, Sangji University) ;
  • Cha, Bae-Chun (College of Life Science & Natural Resources, Sangji University) ;
  • Cho, Soon-Hyun (Central Research Institute, Il-Yang Pharm. Co.)
  • 이은 (상지대학교 생명자원과학대학) ;
  • 최무영 (상지대학교 이공과대학) ;
  • 박희준 (상지대학교 생명자원과학대학) ;
  • 차배천 (상지대학교 생명자원과학대학) ;
  • 조순현 (일양약품 중앙연구소)
  • Published : 1995.06.30
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Abstract

The study on phytochemical analysis and the biological activity of Kalopanacis Cortex was carried out in this research. As a phytochemical result, liriodendrin as a lignan glycoside was isolated and characterized. Two subfraction separated from the acidic substance of $CHCl_3$ fraction were saturated and unsaturated fatty acid, respectively. Saturated fatty acid mixture identified from GC-MS tool was as follows: palmitic acid, stearic acid, arachidic acid, heneicosanoic acid, docosanoic acid, tricosanoic acid, tetracosanoic acid, pentacosanoic acid, hexacosanoic acid and octacosanoic acid. Unsaturated fatty acid was found to be linoleic acid on the basis of spectroscopic method. An active principle of liriodendrin exhibited significant antihepatotoxic activity but failed to show a considerable antiedemic activity. In this paper, the result of writhing test on liriodendrin was also described.

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