Journal of the Korean Society of Food Science and Nutrition (한국식품영양과학회지)

The Korean Society of Food Science and Nutrition (한국식품영양과학회)
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Effect of Jujube Methanol Extract on Benzo(a)pyrene Induced Hepatotoxicity

대추 메탄올 추출액이 Benzo(a)pyrene에 의해 유도된 간기능 장해에 미치는 영향

  • 조수열 (영남대학교 식품영양학과) ;
  • 이윤경 (영남대학교 식품영양학과)
  • Published : 1995.02.01
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Abstract

The protective effect of jujube methanol extract on benzo(a)pyrene(B(a)P)-induced liver injury was studied in rats in vitro and in vivo. Jujube methanol extract significantly recovered the enzyme activities(GOT, GPT, LDH and ALP) and lipid contents(total cholesterol, triglyceride and HDL-cholesterol) changed by B(a)P to normal levels in vivo. in viro experiment jujube methanol extract didn't stimulate hepatocyte proliferation but significantly recovered the enzyme activities(GOT, GPT and LDH) in comparison to group Ⅱ administered B(a)P only. It was suggested that jujube methanol extract have a protective effect on liver injury by B(a)P.

Keywords

References

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