Journal of Nutrition and Health

The Korean Nutrition Society (한국영양학회)
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Effect of Dietary Taurine on Free Amino Acid Concentrations in Blood and Various Tissues of Cats

식이 내의 타우린 함량이 고양이의 혈액 및 주유조직의 유리 아미노산 농도에 미치는 영향

  • 박태선 (연세대학교 생활과학대학 식품영양학과)
  • Published : 1995.10.01
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Abstract

Taurine concentrations in blood and various tissues were measured in cats fed normal trurine diet(0.15% taurine) and trurine-free diet(0% taurine) for 5 weeks and 12 weeks, respectively. Cumulative body weight gain in young cats fed normal taurine diet and taurine-free diet for the initial 5 weeks were 463$\pm$43g and 383$\pm$53g respectively. Taurine concentration was one to two orders magnitude higher in most tissues than in plasma, among which the liver taurine-free diet for 12 weeks resulted in 98% reduction in plasma taurine concentration, 93% reduction in whole blood tarurine concentration, and 40~90% reduction in tissue taurine concentrations compared to the values for normal taurine diet group. Among the tissues tested, taurine depletion was most profound in heart and kidney, while liver and intestine were relatively resistant to taurine depletion. Whole blood taruined concentration appeared to be a better index for the body taurine status of cats as in more closely reflects the rate of taurine depletion in tissues. Taurine depletion in cats significantly increased the concentrations of essential and non-essential free amino acids in liver, while free amino acid concentrations in other tissues were not affected by taurine depletion.

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References

  1. Advences in Pediatrics Taurine. Its biological role and clinical implications Chesney,R.W.;Barness,L.A.(ed.)
  2. Science v.188 Retinal degeneration associated with taurine deficiency in the cat Hayes,K.C.;Carey,R.E.;Schmidt,S.Y.
  3. J Am Vet Med Assoc v.201 no.2 Clinical findings in cats with dilated cardiomyopathy and relationship of findings to taurine deficiency Pion,P.D.;Kittleson,M.D.;Thomas,W.P.;Skiles,M.L.;Rogers,Q.R.
  4. J Nutr v.121 no.8 Dietary taurine content and feline reproduction and outcome Sturman,J.A.;Messing,J.M.
  5. Comp Biochem Physiol v.84B Response of the kitten to dietary taurine depletion : Effects on renal reabsorption, bile acid conjugation and activities of enzymes involved in taurine synthesis Rentschler,L.A.;Hirschberger,L.L.;Stipanuk,M.H.
  6. J Nutr v.106 Dietary influence on bile acid conjugation in the cat Rabin,B.;Nicolosi,R.J.;Hayes,K.C.
  7. Pediatrics v.71 Feeding the low-birth-weight infant.Ⅱ. Effect of taurine and cholesterol supplementation on amino acids and cholesterol Rassin,K.;Gaull,G.E.;Jarvenpaa,A.L.;Raiha,N.C.R.
  8. Pediatr Res v.21 Taurine concentrations in plasma, blood cells, and urine of children undergoing long-term total parenteral nutrition Vinton,N.E.;Laidlaw,S.A.;Ament,M.E.;Kopple,J.D.
  9. Biol Neomates v.32 Is taurine essential for the neonates? Rigo,J.;Senterre,J.
  10. J Pediatr v.116 Taurine depletion in very low birth weight infants receiving prolonged total parenteral nutirition : role of renal immaturity Zelikovic,I.;Chesney,R.W.;Friedman,A.L.;Ahfors,C.E.
  11. Methods in Enzymology v.6 Chromatographic determination of amino acids by the use of automatic recording equipment Moore,S.;Stein,W.H.;Colowick,S.P.(ed.);Kaplan,N.O.(ed.)
  12. Physiol Rev v.73 no.1 Taurine in development Sturman,J.A.
  13. J Nutr v.110 Growth depression in taurine-depleted infant monkeys Hayes,K.C.;Stephan,Z.F.;Sturman,J.A.
  14. J Nutr v.122 High dietry taurine effects on feline tissue taurine concentrations and reproductive performance Sturman,J.A.;Messing,J.M.
  15. J Nutr v.108 Taurine deficiency in the kitten: Exchange and turnover of [$^{35}S$]taurine in brain, retina and other tissues Sturman,J.A.;Rassin,D.K.;Hayes,K.C.;Gaull,G.E.
  16. J Nutr v.121 Tissue taurine content, activity of taurine synthesis enzymes and conjugated bile acid composition of taurine-deprived and taurine-supplemented rhesus monkey infants at 6 and 12 month of age Sturman,J.A.;Messing,J.M.;Rossi,S.S.;Hofmann,A.F.;Neuringer,M.
  17. Arch Biochem Biophys v.210 no.2 Comparative metabolism and taurine-depleting effects of guanidinoethanesulfonate in cats, mice and guinea pigs Huxtable,R.J.;Lippincott,S.E.
  18. Am J Physiol v.263 Constitutive expression of taurine transporter in a human colon carcinoma cell line Tiruppathi,C.;Brandsch,M.;Miyamoto,Y.;Ganapathy,V.;Leibach,F.H.
  19. Current Eye Res v.13 no.7 Molecular identity and calmodulin-mediated regulation of the taurine transporter in a human retinal pigment eptherial cell line Ramamoorthy,S.;Del Monte,M.A.;Leibach,F.H.;Ganapathy,V.
  20. J Nutr v.119 Effect of dietary taurine on renal taurine transport by proximal tubule brush border membrane vesicles in the kitten Park,T.S.;Rogers,Q.R.;Morris,J.G.;Chesney,R.W.
  21. Inter J Neurosci v.5 Effect of intravitreal injections of taurine and GABA on chicken electroretinogram Pasantes-Morales,H.;Bonaventure,N.;Wioland,N.;Mandel,P.
  22. Neurochem Int v.4 Correlations between amino acid concentrations in brains of seizure-susceptible and seizure-resistant rats Huxtable,R.J.;Laird,H.;Bonhaus,D.;Thies,A.C.