Screening of Biologically Active Compounds from various weeds

다양한 잡초로부터 생리활성물질의 탐색

  • Kang, Byeong-Hoa (College of Natural Resources, Korea University) ;
  • Ryoo, In-Ja (Korea Research Institute of Bioscience and Biotechnology, KIST) ;
  • Park, Dong-Jin (Korea Research Institute of Bioscience and Biotechnology, KIST) ;
  • Lee, Hyun-Sun (Korea Research Institute of Bioscience and Biotechnology, KIST) ;
  • Kim, Young-Ho (Korea Research Institute of Bioscience and Biotechnology, KIST) ;
  • Yoo, Ick-Dong (Korea Research Institute of Biotechnology, KIST) ;
  • Kim, Chang-Jin (Korea Research Institute of Bioscience and Biotechnology, KIST)
  • 강병화 (고려대학교 자연자원대학) ;
  • 유인자 (한국과학기술연구원 생명공학연구소) ;
  • 박동진 (한국과학기술연구원 생명공학연구소) ;
  • 이현선 (한국과학기술연구원 생명공학연구소) ;
  • 김영호 (한국과학기술연구원 생명공학연구소) ;
  • 유익동 (한국과학기술연구원 생명공학연구소) ;
  • 김창진 (한국과학기술연구원 생명공학연구소)
  • Published : 1996.10.31

Abstract

To search for bioactive compounds from plant resources, 80% methanol extracts of 46 species of weeds were screened for their activities of antimicrobial, antioxidative, antiblebing, antitumor and herbicidal. Among extracts tested, some showed activities at the concentration of $50\;to\;100\;{\mu}g/ml$. Phryma leptostachya var. asiatica, Aster ageratoides, Centipeda minima, Cirsium pendulum, Lythrum anceps showed antibacterial activity. Penthorum chinense, Lindernia procumbens, Aster ageratoides, Dianthus superbus var. longicalycinus showed antiblebing activity. Phyma leptostachya var. asiatica, Juncus effusus var. decipiens, Lindernia procumbens, Aster ageratoides, Dianthus superbus var. longicalycinus, Viscum album var. coloratum showed antitumor activity. Juncus effusus var. decipiens, Hypericum ascyron, Juncus papillosus, Inula britannicar var. chinensis, Scirpus wichurae, Hypericum laxum showed antioxidant activity.

다양한 잡초로부터 유용 생리활성물질을 탐색하고자 46종 잡초의 methanol 추출액을 대상으로 $50{\sim}100\;{\mu}g/ml$ 농도로 실험한 결과, 항균 활성에 있어서는 파리풀, 까실쑥부쟁이, 중머리대가리, 큰엉겅퀴, 부처꽃 등이 antobleb 활성에 있어서는 낙지다리, 밭뚝외풀, 까실쑥부쟁이, 술패랭이꽃 등이 항암활성에 있어서는 파리풀, 골풀, 밭뚝외풀, 까실쑥부쟁이, 술패랭이꽃, 겨우살이 등이 항산화활성에 있어서는 골풀, 물레나물, 청비녀골풀, 금불초, 방울고랭이, 좀고추나물 등이 비교적 강한 활성을 나타내었다.

Keywords