Effects of Cervi Cornu Aqua-Acupuncture on Lipid Metabolisms and Osteoporosis in Ovariectomized Rats

녹용약침자극(鹿茸藥鍼刺戟)이 난소적출(卵巢摘出) 흰쥐의 지질(脂質) 및 골대사(滑代謝)에 미치는 영향(影響)

  • Abadjieva, Daniela K. (Department of Acupuncture and Moxibustion, College of Oriental Medicine, KyungHee University) ;
  • Kang, Sung-Keel (Department of Acupuncture and Moxibustion, College of Oriental Medicine, KyungHee University)
  • Published : 1996.10.30

Abstract

In order to study the effect of aqua-acupuncture with Cervi Cornu (C.C.) extract solution manufactured by water-alcohol method on the lipid metabolism and osteoporosis, C.C. aqua-acupuncture was carried out every two days for 60 days on the corresponding bilateral loci of Shinsu (BL23), Taejo (BL11), and Hyonjong (GB39) from the 10th day after the ovariectomy for induced osteoporosis and thereafter the level of serum triglyceride, LDL, Ca, phosphorus and osteocalcin, as well as urine hydroxyproline were measured in the ovariectomized rats. The rats being studied were divided into a normal group (sham operation group), a control group (ovariectomized group), and a C.C. aqua-acupuncture group (group with C.C. aqua-acupunctured to the points of Shinsu, Taejo, and Hyonjong every two days for 60 days from the 10th day after the ovariectomy). The following results were obtained: 1. The serum triglyceride indicated an inhibited increase with statistical significance in the C.C. aqua-acupuncture group compared with the control group. 2. The serum LDL indicated an inhibited increase without any statistical significance in the C.C. aqua-acupuncture group compared with the control group. 3. The serum Ca showed an inhibited decrease without any statistical significance in the C.C. aqua-acupuncture group compared with the control group. 4. The serum phosphorus showed an inhibited decrease with statistical significance in the C.C. aqua-acupuncture group compared with the control group. 5. The serum osteocalcin indicated an inhibited decrease without any statistical significance in the C.C. aqua-acupuncture group compared with the control group. 6. The urine hydroxyproline showed an inhibited increase with statistical significance in the C.C. aqua-acupuncture group compared with the control group.

Keywords

References

  1. 골다공증(골조송증) 대한골대사학회
  2. 동의생리학 대한동의생리학회
  3. 동의신계학 두호경
  4. 임상내분비학 민헌기
  5. 병리학 백윤기
  6. 전통약물로부터 신약개발 연구법 서울대학교 천연물과학 연구소
  7. 임상화학 이귀녕;김진규
  8. 임상병리파일 이귀녕;이종순
  9. 임상병리검사법 이삼열(외)
  10. 병리학 이중달
  11. 최신침구학 최용태(외)
  12. 침구학(상) 최용태(외)
  13. 東醫寶鑑外形篇 許浚
  14. 대한침구학회지 v.15 no.2 골다공증의 침구치료에 관한 문헌적 고찰 강성길;박영배;안현석
  15. 대한산부인과학회지 v.31 no.6 폐경기 여성에서의 증상,지질변화 및 호르몬 변화에 대한 연구 김병창;김동호;허민
  16. 대한의학협회지 v.32 no.1 고령환자의 정형외과적 치료 문명상;우영균
  17. 대한내과학회지 v.34 no.4 골조송증 민헌기
  18. 대한내분비학회지 v.4 no.1 골다공증 치료의 기본개념 민헌기
  19. 대한정형외과학회지 v.28 no.3 골조송증에서의 척추골절 석세일;이춘기;강홍식;이지호;민학진;차상훈;정용진
  20. 경희의학 v.11 no.3-4 실험적 골다공증에 미치는 加味二仙湯의 효능에 관한 組織計測學的 硏究 신현대;정석희;손낙원
  21. 대한내과학회잡지 v.34 no.4 한국여성골조송증환자들에서 보인 골조송증 위험인자(예보) 임승길;정현철;이미경;김현만;이현철;허갑범;김남현;박병문
  22. 대한정형외과학회지 v.27 no.1 이중에너지 방사선 흡수계측법을 이용한 원발성 골조송증에 의한 척추골절의 골밀도 측정 장준섭;문성환
  23. 대한스포츠의학지 v.10 no.2 골다공증 최장석
  24. 대한내분비학회지 v.4 no.1 한국인 갱년기여성의 골밀도 및 호르몬 변화에 관한 연구 한인권;박원근;최웅환;신현호;김선우
  25. 難經校注 凌耀昌
  26. 黃帝內經素問今釋 王琦(外篇)
  27. 婦女更年期老年期病症 袁耀夢(主編)
  28. 聖濟總錄 政和奉勅(撰);吳錫璜(編)
  29. 普濟方 朱肅撰
  30. 圖設漢方醫學大辭典 IV 陳存仁
  31. 實用中西醫結合雜誌 v.6 no.5 腎虛型高血壓與骨鑛物含量硏究 李士林;王久春;克丙申;李金華;趙玉堂
  32. 中國中西醫結合雜誌 v.13 no.3 絶經早晩對骨密度的影響 遲煥海;郭素華;楊定綽;張紀淮;李秀均
  33. 中國中西醫結合雜誌 v.14 no.3 腎虛證患者骨鑛物含量改變的初步探討 蔡新吉;張燕;黃世林
  34. 中國中西醫結合雜誌 v.13 no.9 補腎中藥片對圍絶經期婦女骨質疏松代謝的影響 黃艶紅;葉雪淸
  35. Am. J. Nutrition v.10 Influence of diet on serum lipid in south African White and Bantu prisoners Antonis, A.;Bersohn, I.
  36. Circulation v.55 HDL-cholesterol and other lipids in coronary heart disease Castelli, W.P.;Doyle, J.T.;Gordon, T.(et al.)
  37. Am. J. Cardiol. v.37 Some leassons in cardiovascular epidemiology from Famington Kannel, W.B.
  38. Orthop Clin North AM v.15 Osteoporosis Lane, J.M.;Vigorita, V.J.
  39. Fertility and Sterility v.59 no.4 Osteioporosisl;screening, prevention and management Notelovitz, M.
  40. Br. J. Obstet. Gynecol. v.90 Lipids and lipoproteins in women after oophorectomy and the response to estrogen therapy Notelovitz, M.;Gudat, J.C.;Ware, M.D.;Dougnerty, M.D.
  41. Clinical Chemistry v.35 Radioimmunoassay of osteocalcin with polyclonal and monoclonal antibodies Power, M.J.;Gosling, J.P.;Fottrell, P.F.
  42. Am. J. Med. v.91 no.5B Effect of calcitonin on bone mass and fracture rate Reginster, J.Y.
  43. N. Engl. J. Med. v.327 no.9 The prevention and treatment of osteoporosis Riggs, B.L.;Melton, L.J.
  44. Postgraduate Medicine v.93 no.8 Primary Osteoporosis Susan, H. Allen