Effect of Dietary Fiber on the Serum Lipid Level and Bowel Function in Aged Rats

노화된 흰쥐에서 식이섬유질원이 첨가된 식이가 혈청지질과 장기능에 미치는 효과

  • 박은영 (한양대학교 가정대학 식품영양학과)
  • Published : 1996.11.01

Abstract

This study was performed to investigate the influence of dietary fibers on the serum lipid level and bowel function in aged rats. Fiber sources of experimental diets were made from mugwort(M), butterbur(B), apple(A), sea mustard(S) by drying and milling. Each of fiber sources was mixed into the diet at the level of 5, 15% of diet. Sprague-Dawley strain, 13 month old male rats were divided into 9 groups by randomized complete block design : C, M5, B5, A5, S5, M15, B15, A15, S15. The animals were fed ad libitum each of experimental diets for 4 weeks. Control group showed lower food intake compare to the other groups. There were no significant difference between 5% groups and 15% groups in food intake. Fecal weight, dry fecal weight and fecal water content of control group were significantly lower than those of experimental groups, and fecal water content was increased by increasing level of dietary fibber. Apple group showed the lowest values, sea mustard group showed the highest. The shorter transit time was observed in the group of higher intake of dietary fiber. At the same level of dietary fiber, transit time of sea mustard group was shorter than the other groups. With increasing age, serum triglycerides, total cholesterol were increased and HDL-cholesterol was decreased. Fiber fed groups showed lower serum TG, TC and higher HDL-c level compare to the control group. Absorption rates of calcium, magnesium and phosphorus was tend to be lower in the group fed dietary fiber sources than control group. Mucosa weight and maltase activity in the small intestine were decreased by increasing age. As intake of dietary fiber increaed, mucosa weight in the small intestine was not different but maltase activity was decreased.

Keywords

References

  1. 장래인구추이 경제기획원 조사통계청
  2. Am J Clin Nutr v.55 Changes in life expectancy 1900-1990 Kinsella,K.G.
  3. Am J Clin Nutr v.36 Nutrition, aging and longevity Harper,A.E.
  4. J Nutr v.123 Changes in plasma and hepatic lipids, small intestinal histology and pancreatic enzyme activity due to aging and dietary fiber in rats Schneeman,B.O.;Richter,D.
  5. Am J Clin Nutr v.29 Definition of dietary fiber and hypotheses that it is a protective factor in certain diseases Trowell,H.
  6. Definitions of dietary fibre and fibre-depleted foods : in Dietary fibre, fibre-depleted foods and disease Trowell,H.;Burkitt,D.
  7. Am J Clin Ntr v.55 Changes in gastrointestinal function attributed to aging Russell,R.M.
  8. Am J Clin Nutr v.31 Nutritional implications of dietary fiber Cummings,J.H.
  9. J Nutr v.110 Effect of dietary fiber on mineral absorption in growing rats Hoene,A.E.;Schelenz,R.
  10. J Nutr v.119 AIN-76 diet : Should we change the formulation? Reeves,P.G.
  11. J of AOAC v.56 Collaborative study of acid-detergent fiber and lignin Van Soest P.J.
  12. Cereal foods world v.35 Determination of insoluble, soluble, and total dietary fiber : collaborative study of a rapid gravimetric method Mongeau,R.;Brassard,R.
  13. Gut v.10 A new method for studying gut transit times using radiopaque markers Heanton,J.M.;Lennard-Jones J.E.;Young,A.C.I.
  14. Kor J Nutr v.25 no.1 The importance of total dietary fiber in human nutrition and health Gordon,D.T.
  15. J Am Diet Assoc v.88 no.8 Does dietary fiber affect food intake and body weight? Stevens,J.
  16. Gut v.16 The effect of wheat bran on intestinal transit Payler,D.K.;Pomare,E.W.;Heaton,K.W.;Harvey,R.F.
  17. Cancer v.28 Epidemiology of cancer of colon and rectum Burkitt,D.P.
  18. Gut v.20 Water-holding by dietary fibre in vitro and its relationship to faecal output in man Stephen,A.M.;Cummings,J.H.
  19. Lancet v.2 Diverticular disease of the colon : a disease of this century Painter,N.S.
  20. J Nutr v.123 Vegetable fiber fermentation by human fecal bacteria : cell wall polysaccharide disappearance and short-chain fatty acid production during in vitro fermentation and water-holding capacity of unfermented residuces Bourquin,L.D.;Titgemeyer,E.C.;Fahey,G.C.
  21. Am J Clin Nutr v.32 Hypochole-sterolemic action of dietary fiber unrelated to bulking effect Jenkins,D.A.;Reynolds,D.;Leeds,A.R.;Waller,A.L.;Cummings,J.H.
  22. Dietary fiber in health and disease Vahouny,G.V.;Kritchevsky,D.
  23. 한국노화학회지 v.4 no.2 노화촉진마우스(SAM) 뇌의 연령관련 생리적 변화에 관한 연구 최진호;유병팔
  24. 한양대 식품영양학과 석사학위논문 식이섬유질의 종류가 흰쥐의 혈청지질농도와 장기능에 미치는 영향 김미정
  25. Kor J Nutr v.25 no.6 Total dietary fiber and mineral absorption Gordon,D.T.
  26. Am J Clin Nutr v.36 no.10 Factors contributing to calcium loss in aging Spencer,H.;Kramer,L.;Osis,D.
  27. J Nutr v.113 The action of cellulose on intestinal mucosa and element absorption by the rat Gordon,D.T.;Williford,C.B.;Ellersieck,M.R.
  28. Am J Clin Nutr v.33 Influence of refined cellulose on human bowel function and calcium and magnesium balance Slavin,J.L.;Marlett,J.A.
  29. Comp Biochem Physiol v.101 no.3 Diet fatty acid composition, age and rat jejunal microvillus enzyme activities Brenard,A.
  30. J Nutr v.117 Intestinal structural change in African green monkey after long term psyllium or cellulose feeding Paulini,I.;Mehta,T.;Hargis,A.