YAKHAK HOEJI (약학회지)
- Volume 40 Issue 5
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- Pages.582-590
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- 1996
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- 0377-9556(pISSN)
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- 2383-9457(eISSN)
Screening of the Antifungal Activity from Natural Products against Candida albicans and Penicillium avellaneum
Candida와 Penicillium 속 진균에 대한 천연물의 항진균 효과 검색
- Min, Byeong-Seon (R & D Center, Kolon Pharmaceuticals INC.) ;
- Bang, Gyu-Ho (R & D Center, Kolon Pharmaceuticals INC.) ;
- Lee, Jun-Seong (College of Pharmacy, Chungnam National University) ;
- Bae, Gi-Hwan (College of Pharmacy, Chungnam National University)
- Published : 1996.10.01
Abstract
For the research of antifungal active constituents from natural products, 226 plants were extracted with ether and methanol, separately, and screened antifungal activity against Candida albicans and Penicillium avellaneum cells. The results demonstrated that 30 samlpes showed antifungal activity in ether or methanol extracts and 17 samples in ether extracts and 20 samples in methanol extracts against C. albicans. Against P. avellaneum, 19 samlpes showed antifungal activity in ether or methanol extracts and 17 samples in ether extracts and 11 samples in methanol extracts, respectively. The antifungal activity of natural products against C. albicans were showed more sensitive than P. avellaneum, and the polarity of the solvent was not specific in antifungal activity.