Effect of Lxeris Sonchifolia H. on Serum Lipid Metabolism in Hyperlipidemic Rats

고들빼기의 급여가 고지혈증 흰쥐의 지질대사에 미치는 영향

  • 임상선 (경상대학교 식품영양학과)
  • Published : 1997.10.01

Abstract

The effect of lxeris sonchifolia H.(godulbaegi) on lipid metabolism were studied in S. D. rats. Twenty four rats were divided into four groups and fed diets containing 1 % cholesterol, 0.25% sodium cholate, 10% coconut oil and 5% lard(control group)f for 3 weeks. An experimental diet group was added with 5% leaf(PL group) or root powder(PR group) of godulbaegi. The lipid components and enzyme activites of serum and liver were assayed. The concentrations of total cholesterol, triglyceride and phospholipid were significantly lower in the PL and PR groups than in the control group. The levels of HDL-cholesterol were not significant but showed somewhat higher values in the PL and PR groups compaired with the control. The activities of glutamic oxaloacetic transminase(GPT) and glutamic pyruvic transaminase(GPT) were significantly lower in the PL and PR groups compaired with the control. In view of these results Godulbaegi is expected to be an effective food in preventing and improving the hyperlipidemic state.

Keywords

References

  1. 韓國産菊花科 植物에 對한 本草學的 硏究 朱榮丞
  2. Am J Clin Nutr v.52 Oat-bran cereal lowers serum total and LDL-cholesterol in hypercholesterolemic men Anderson,J.W.;Spencer,D.B.;Hamilton,C.C.
  3. Arterosclerosis v.9 Dietary fish oil increases the conversion of VLDL apo B to LDL apo B Huff,M.W.;Telford,D.E.
  4. 日本營養食糧學會誌 v.37 no.4 ラットの 食餌性 コレステロ-血症に 及しはすスビ ルリナの 影響 加藤敏光;竹本和夫;片山博雄;矮原祥子
  5. Br J Nutr v.42 The role of saponin on lower plasma cholesterol concentration Oakenfull,D.G.;Fenwick,D.E.;Hood,R.L.;Topping,D.L.;Ilman,R.J.;Storer,G.B.
  6. J Nutr v.107 Interrelated effects of food lipids on steroid metabolism in rats O'Brien,B.C.;Skutches,C.L.;Henderson,G.R.;Reiser,R.
  7. 한국영양학회지 v.30 no.1 고들빼기 식이가 간독성을 유발한 흰쥐의 효소활성에 미치는 영향 배송자;김남흥;고진복;노승배;정복미
  8. 한국식품영양과학회지 v.26 no.1 고들빼기 잎 추출물이 흰쥐의 사염화탄소에 의한 간손상에 미치는 영향 배송자;김남흥;하배진;정복미;노승배
  9. Am J Clin Pathol v.28 A colorimetric method for the determination of serum glutamic oxaloacetic and glutamic pyruvic transaminase Reitman,S.;Frankel,S.
  10. Science v.120 Transaminase activity in human blood La Due,J.S.;Wrobewski,F.;Karmen,A.
  11. 한국식품영양과학회지 v.26 no.1 참취 및 씀바귀의 성분 조성과 혈청지질 저하작용에 대한 연구 임상선;이종호
  12. 한국식품영양과학회지 v.26 no.3 돌해파리의 성분조성 및 혈청지질 저하작용에 대한 연구 강문선;임상선;이종호
  13. J Nutr v.122 Dietary soluble fiber and cholesterol affect serum cholesterol concentration, hepatic portal venous short-chain fatty acid concentration and fecal sterol excretion in rats Arjmandi,B.H.;Ahn,J.;Nathani,S.;Reeves,R.D.
  14. 한국영양식량학회지 v.21 no.3 Ixeris 속 식물의 약화학적 연구 1. 고들빼기의 고콜레스테롤혈증 개선 효과 양한석;서석수;이경희;이지현;최재수
  15. Am J Clin Nutr v.55 Effect of oat bran, rice bran, wheat fiber and wheat germ on postprandial lipemia in healthy adults Cara,L.;Dubois,C.;Borel,P.;Armand,M.;Senft,M.;Portugal,H.;Pauli,A.M.;Bernard,P.M.;Lairon,D.
  16. J Nutr v.113 Effect of blackgram fiber on hepatic hydroxymethylglutaryl CoA reductase activity, cholesterogenesis and cholesterol degradation in rats Thomas,M.;Leelamma,S.;Kurup,P.A.
  17. Am J Clin Nutr v.47 Dietary fiber and intestinal adaptation : Effects on lipid absorption and lyphatic transport in the rat Vahouny,G.V.;Satchithanandam,S.;Chen,I.;Tepper,S.A.;Kritchevsky,D.;Lightfoot,F.G.;Cassidy,M.M.
  18. J Nutr v.122 Soluble dietary fiber and cholesterol influence in vivo hepatic and intestinal cholesterol biosynthesis in rats Arjmandi,B.H.;Craig,J.;Nathani,S.;Reeves,R.D.
  19. Nutr Rep Int v.29 Influence of oat and wheat bran on cholesterolemia in rats Kritchevsky,D.;Tepper,S.A.;Goodman,G.T.;Weber,M.M.;Klurfed,D.M.
  20. 檢査成績의 臨床的 活用 金箕洪
  21. 한국영양학회지 v.14 no.3 食餌性 纖維素가 콜레스테롤 食餌 흰쥐의 血淸 및 肝臟脂質에 미치는 影響 박미리;조수열
  22. J JAN Food Nutr v.45 no.1 Effects of long term administration of indigestable dextrin as soluble dietary fiber on lipid and glucose metabolism Normura,M.;Nakajima,Y.;Abe,H.
  23. 한국영양학회지 v.30 no.1 쑥 및 엉겅퀴가 식이성 고지혈증 흰쥐의 혈청지질에 미치는 영향 임상선;이종호