Journal of Nutrition and Health

The Korean Nutrition Society (한국영양학회)
권호 표지

The Effects of Dietary Shellfish on Lipid Metabolism in Rats Fed High-Fat Supplement

고지방식이를 급여한 흰쥐의 패류식이 급여 효과

  • Published : 1998.10.01
Download PDF
⟨ Previous Next ⟩

Abstract

This study was conducted to investigate the effects of shellfish on lipid metabolism in rats fed high fat supplements. Male sprague-dawley rats weighting approximately 165g were fed a basal diet, a high fat diet, or a high fat diet plus shellfish for 4 weeks. The shellfishes on the were oyster, hard-shelled mussel, little neck clam, and march clam. Alfter 4 weeks high fat diet, supplementation of 20% lard significantly increased plasma. GOT, GPT, ${\gamma}$-GTP , and liver triglyceride (TG). Plasma GOT, GPT, ${\gamma}$-GTP , triglyceride, and total cholestrerol levels were significantly lower in shellfish groups than in basal and high-fat groups regardless of high-fat supplementation (p<0.05). The total lipid and cholesterol content in liver showed similar results(p<0.05). There were no differences in glucose, HDL-cholesterol in plasma and total cholesterol and total lipid in liver between basal and high-fat supplemented diets. Liong chain fatty acids, specific components of shellfishes group, were exclusively higher than in basal and high-fat diets, and were most well-reflected in liver and plasma. From the above results, the hypolipidemic effects of shellfish were detected in the process of inducing hyperlipidemia by high-fat supplement.

Keywords

References

  1. Seafoods and fish oils in human oils in human health and disease John,E.K.
  2. Bull Korean Fish Soc v.26 no.2 Comparison of Food composition in the raw,cooked meat and cooked meat extracts of cookle shell Kim,K.S.
  3. Kook Min University Master's Degree Thesis Effect of DHA and environmental enrichment on brain fatty acid composition and acetylcholinesterase activity Kim,M.J.
  4. Pukyong National University Master's Degree Thesis Phusiological effects of the taurine supplmented diet on rats fed on the high fat diet compared to spontaneous hypertensive rats Kim,E.J.
  5. Seafoods and fish oils in human health and disease John,E.K.
  6. Korea University Master's degree thesis A study on fatty acid pattern in brain and liver tissues of developing chicken embryos Choi,J.H.
  7. J Biol Chem v.226 A simple method for the isolation and purification of total lipid from animal tissues Folch,JML.;Sloan-Stanley,G.H.
  8. J Lipid Res v.27 Direct transesterification of all classes of lipid in a one-step reaction Lepage,G.;Roy,C.C.
  9. Lipids. v.25 Fatty acid content of marine oil capsules Chee,KM.;Gang,XJ.;Rees,DMG.;Meydani,M.;Ausman,L.;Johnson,J.;Singuel,EN.;Schaefer,E.
  10. Korea J Nutririon v.6 no.1 Changes in the lipid composition and some enzyme activities in the rat liver as affected by diets Kim,Y.K.
  11. Nutrition Research v.11 Dietary cysteine/methionine ratios and taurine supplementation : Effect on rat growth, amino acids and bile acids Sarwar,G.Peace R.W.;Botting,H.G.
  12. Bochemistry v.30 Taurine-conjugated bile acid act as Ca^2x ionophores Zimniak,P.;Radomonska,A.;Lester,R.
  13. J Nutr Sci Vitaminol v.35 Effect of dietary pantethine level on drug-metabolizing syatem in the liver of rats orally administered varying amounts of autoxidized linoleate Hiramatsu,N.;Kishida,T.;Natake,M.
  14. Physiological Reviews v.72 no.1 Physiological action of taurine Huxtable,R.J.
  15. J Nutr Sci Vitaminol v.37 Cholesterol-Lowering effect of agemaki, a kind of shellfish, in mice Teruyosh,Y.;Noriyuki,E.;Kyosuke,Y.
  16. J Nutr v.116 Diets varying in linoleic and linolenic acid content alter liver plasma membrane lipid composition and glucagon- stimulated adenylate cyclase activity Morson,L.A.;Clandinin,M.T.
  17. J Clin Invest v.76 Metabolism and effects on platelet function of the qurified eicosapentaenoic and docosahexaenoic acids in humans Von Schacky,C.;Weber,P.C.
  18. Br J Nutr v.68 The influence of a fish oil high in docosahexaenoic acid on plasma lipoprotein and vitamin E concentration and haemostatic function in healthy male volunteers Sander,T.A.B.;Hinds,A.
  19. Am J Clin Nutr v.31 The influence of dietary mackerel oil on the condition of organs and on blood lipid composition in the young growing pig Ruiter,A.;Jongbloed,A.W.;van Gent,C.M.;Danse,L.H.J.C.;Metz,S.H.M.
  20. Doctor's Degree Thesis, Sookmyung Women's University Effect of dietary fish oil and casein on lipid me tabolism of plasma and tissues in young chicks Choi,I.S.
  21. Am J Path v.48 The ultrastructure of fatty liver induced by prolonged ethanol ingestion Arai,M.;Gordon,E.R.;Gottilieb,L.S.
  22. Master's Degree Thesis, Seoul Woman's University Effect of chronic feeding and 2-acethlaminofluorene treatment on hepatic mitochondrial ATPase activity and membrane lipid composition in rats Ryu,S.Y.