Journal of Korean Medical Science

Korean Acad Medical Sciences (대한의학회)
권호 표지

Clinical Characteristics of Acute Viral Lower Respiratory Tract Infections in Hospitalized Children in Seoul, 1996-1998

Ahn, Kang-Mo;Chung, So-Hee;Chung, Eun-Hee;Koh, Young-Jae;Nam, Seung-Yeon;Kim, Jeong-Hee;Son, Jin-A;Park, Jin-Young;Lee, Nam-Yong;Lee, Sang-Il

  • Published : 19990800

⟨ Previous Next ⟩

Abstract

This study was performed to investigate the etiologic agents, age distribution, clinical manifestations and seasonal occurrence of acute viral lower respiratory tract infections in children. We confirmed viral etiologies using nasopharyngeal aspirates in 237 patients of the ages of 15 years or younger who were hospitalized for acute lower respiratory tract infection (ALRI) from March 1996 to February 1998 at Samsung Seoul Hospital, Seoul, Korea. The overall isolation rate was 22.1%. The viral pathogens identified were adenovirus (12.7%), influenza virus type A (21.1%), -type B (13.9%), parainfluenza virus type 1 (13.5%), -type 2 (1.3%), -type 3 (16.0%) and respiratory syncytial virus (21.5%). The occurrence of ALRIs was highest in the first year of life, although parainfluenza virus type 1 infection occurred predominantly in the second year of life and influenza virus caused illnesses in all age groups. The specific viruses are frequently associated with specific clinical syndromes of ALRI. The respiratory agents and associated syndromes frequently have characteristic seasonal patterns. This study will help us to estimate the etiologic agents of ALRI, and establish a program for the prevention and treatment. An annual nationwide survey is necessary to understand the viral epidemiology associated with respiratory illnesses in Korea.

Keywords

References

  1. Bull WHO v.56 Acute respiratory infections: a review Bulla, A.;Hitze, K.L.
  2. N Engl J Med v.310 Acute respiratory infections in children: a global public-health problem Chretien, J.;Holland, W.;Macklem, P.;Murray, J.;Woolcock, A.
  3. Pediatr Infect Dis J v.5 Etiology of severe pneumonia in children in developing countries Shann, F.
  4. Pediatr Infect Dis J v.8 ？Problems in determining the etiology of community-acquired childhood pneumonia Issacs, D.
  5. Pediatr Infect Dis J v.14 ？Viral etiology and epidemiology of acute lower respiratory tract infections in Korean children ？Yun, B.Y.;Kim, M.R.;Park, J.Y.;Choi, E.H.;Lee, H.J.;Yun, C.K.
  6. J Pediatr v.108 ？Acute lower respiratory tract infections in nonhospitalized children ？Denny, F.W.;Clyde, W.A. Jr.
  7. Am J Respir Crit Care Med v.152 ？The clinical impact of human respiratory virus infections ？Denny, F.W.
  8. Am J Dis Child v.145 The causes of hospital-treated acute lower respiratory tract infection in children ？Nohynek, H.;Eskola, J.;Laine, E.;Halonen, P.;Ruutu, P.;Saikku, P.;Kleemola, M.;Leinonen, M.
  9. J Pediatr v.95 The etiologic and epidemiologic spectrum of bronchiolitis in pediatric practice ？Henderson, F.W.;Clyde, W.A.;Collier, A.M.;Denny, F.W.
  10. Bull WHO v.60 Viral agents of acute respiratory infections in young children in Kuala Lumpur Ong, S.B.;Lam, K.L.;Lam, S.K.
  11. Lacet v.2 Aetiology of pneumonia in children in Goroka Hospital, Papua New Guinea Shann, F.;Gratten, M.;Germer, S.;Linnemann, V.;Hazlett, D.;Payne, R.
  12. N Engl J Med v.288 Epidemiology of acute lower respiratory disease in children Glezen, W.P.;Denny, F.W.
  13. Am J Epidemiol v.122 Acute respiratory disease hospitalization as a measure of impact of epidemic influenza Perrotta, D.M.;Decker, M.;Glezen, W.P.
  14. J Infect Dis v.155 Acute respiratory disease associated with influenza epidemics in Houston Glezen, W.P.;Decker, M.;Joseph, S.W.
  15. Postgrad Med J v.49 Adenovirus infections Pereira, M.S.
  16. Am J Epidemiol v.114 The epidemiology of tracheobronchitis in pediatric practice Chapman, R.S.;Henderson, F.W.;Clyde, W.A. Jr.;Collier, A.M.;Denny, F.W.
  17. Am J Epidemiol v.113 Pneumonia: an eleven-year study in a pediatric practice Murphy, T.F.;Henderson, F.W.;Clyde, W.A. Jr.;Collier, A.M.;Denny, F.W.
  18. Pediatrics v.71 Croup: an 11-year study in a pediatric practice Denny, F.W.;Murphy, T.F.;Clyde, W.A. Jr.;Collier, A.M.;Henderson, F.W.
  19. J Korean Pediatr Soc v.39 Ten cases of severe adenoviral pneumonia in the spring, 1995 Kim, J.H.;Lee, S.I.;Lee, M.H.;Kang, I.S.;Lee, H.J.;Kim, B.K.;Suh, Y.L.
  20. Korean J Pediatr Infect Dis v.3 Clinical review of pediatric adenoviral lower respiratory infection Son, J.A.;Lee, S.I.;Lee, N.Y.;Kim, J.H.
  21. Am J Roentgenol v.170 ？Epidemic adenoviral lower respiratory tract infection in pediatric patients: radiographic and clinical characteristics ？Han, B.K.;Son, J.A.;Yoon, H.K.;Lee, S.I.
  22. N Engl J Med v.277 ？Bacterial-viral interrelations in respiratory infections in children Nichol, K.P.;Cherry, J.D.
  23. Pediatr Infect Dis J v.3 ？Pathogens associated with acute lower respiratory tract infection in youg children ？Paisley, J.W.;Lauer, B.A.;McIntosh, K.
  24. Pediatrics v.78 Use of bacterial antigen detection in the diagnosis of pediatric lower respiratory tract infections Ransey, B.W.;Marcuse, E.K.;Foy, H.M.
  25. J Pediatr v.111 Pneumonia in pediatric out-patients: cause and clinical manifestations Turner, R.B.;Lande, A.E.;Chase, P.
  26. Pediatr Infect Dis J v.8 Mixed baterial and viral infections are common in children Hietala, J.;Uhari, M.;Tuokko, H.;Leinonen, M.
  27. Pediatr Infect Dis J v.8 Bacterial coinfection in children hospitalized with respiratory syncytial virus infections Korppi, M.;Leinonen, M.;Koskela, M.;Makela, H.;Launiala, K.