Archives of Pharmacal Research

The Pharmaceutical Society of Korea (대한약학회)
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Antioxidative flavonoids from the Leaves of Morus alba

  • Kim, Sun-Yeou (Dept. of Sericulture & Entomology, National Institute Agricultural Science and Technology, RDA) ;
  • Gao, Jian Jun (Dept. of Sericulture & Entomology, National Institute Agricultural Science and Technology, RDA) ;
  • Lee, Won-Chu (Dept. of Sericulture & Entomology, National Institute Agricultural Science and Technology, RDA) ;
  • Ryu, Kang-Sun (Dept. of Sericulture & Entomology, National Institute Agricultural Science and Technology, RDA) ;
  • Lee, Kang-Ro (College of Pharmacy, SungKyunKwan University) ;
  • Kim, Young-Choong (College of Pharmacy, Seoul National University)
  • Published : 1999.02.01
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Abstract

Nine flavonoids (1-9) were isolated from the leaves of Morus alba (Moraceae). The structures of compounds were determined to be kaempferol-3-O-$\beta$-glucopyranoisde (astragalin, 1) kaempferol-3-O-(6"-O-acetyl)-$\beta$-D-glucopyranoside (2), quercetin-3-O-(6"-O-acetyl)-$\beta$-D-glucopyranoside (3), quercetin-3-O-$\beta$-D-glucopyranoside (4), kaempferol-3-O-$\alpha$-L-rhamnopyranosyl-(1 6)-$\beta$-D-glucopyranoside (5), quercetin-3-O-$\alpha$-L-rhamnopyranosyl-(1 6)-$\beta$-D-glucopyranoside (rutin, 6), quercetin-3-O-$\beta$-D-glucopyranosyl-(1 6)-$\beta$-D-glucopyranoside (7), quercetin-3,7-di-O-$\beta$-D-glucopyranoside (8) and quercetin (9) on th basis of spectroscopic and chemical studies. Compounds 7 and 9 exhibited significant radical scavenging effect on 1,1-diphenyl-2-picryl-hydrazyl radical.

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