Archives of Pharmacal Research

The Pharmaceutical Society of Korea (대한약학회)
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Cytotoxicity of Urushiols Isolated from Sap of Korean Lacquer Tree (Rhus vernicifera Stokes)

  • Hong, Dong-Ho (Korea Research Institute of Bioscience and Biotechnology) ;
  • Han, Sang-Bae (Korea Research Institute of Bioscience and Biotechnology) ;
  • Lee, Chang-Woo (Korea Research Institute of Bioscience and Biotechnology) ;
  • Park, Se-Hyung (Korea Research Institute of Bioscience and Biotechnology) ;
  • Jeon, Young-Jin (Korea Research Institute of Bioscience and Biotechnology) ;
  • Kim, Myong-Jo (Korea Research Institute of Bioscience and Biotechnology) ;
  • Kwak, Sang-Soo (Korea Research Institute of Bioscience and Biotechnology) ;
  • Kim, Hwan-Mook (Korea Research Institute of Bioscience and Biotechnology)
  • Published : 1999.12.01
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Abstract

Cytotoxicities of four urushiols, congeners isolated from the sap of Korean lacquer tree (Rhus vernicifera Stokes), to 29 human cancer cell lines originated from 9 organs were evaluated. Their values of 50% growth inhibition were below $4{\mu}g/ml$, and showed cell line specific cytotoxicity. The present results is the first report on the cytotoxicity of urushiols suggesting that they would have an anticancer activity to human cancer cells.

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