Journal of the Korean Society of Food Science and Nutrition (한국식품영양과학회지)

The Korean Society of Food Science and Nutrition (한국식품영양과학회)
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Effects of Chitin and Chitosan on Lipid Metabolism in Rats

Chitin.Chitosan이 흰쥐의 콜레스테롤 대사에 미치는 영향

  • 박정로 (순천대학교 식품영양학과) ;
  • 문일식 (순천대학교 화학공학과) ;
  • 최성희 (충남대학교 농업과학연구소) ;
  • 손미예 (경상대학교 식품영양학과)
  • Published : 1999.04.01
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Abstract

The effects of chitin and chitosan on the contents of plasma and liver lipids and the fecal excretion of neutral and acidic steroids were investigated in rats fed with atherogenic diet. Dietary chitin did not affect plasma total cholesterol, LDL cholesterol and HDL cholesterol, while chitosan diet de creased total cholesterol and LDL cholesterol. Plasma content of triglyceride was reduced signif icantly by chitin diet but not by chitosan. Increases in fecal weight were observed in rats fed with either chitin or chitosan, and the increase was greater with chitosan than with chitin. Dietary chitosan resulted in an increase of fecal excretion of neutral steroids without any changes in the excretion of acidic sterols. Putting the results together, dietary chitosan reduces plasma cholesterol probably due to the reduction of cholesterol absorption. The decrease in plasma triglyceride level by dietary chitin requires further research to understand the mechinism.

Keywords

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