A Comparative Study on Serum Lipid Levels in Drinker and Non-drinker

알코올 섭취자와 비섭취자의 혈청 지질 수준에 대한 비교연구 -충남 일부지역 남자공무원을 대상으로-

  • Published : 1999.07.01

Abstract

This study was carried out to examine the effects of alcohol on serum lipid levels. Subjects of this study were 50 military officers living in Honsung, Korea, 25 of whom consumed alcohol on a regular basis and 25 of whom did not. All subjects were previously informed of the purpose of the study and the methods of food intake reporting and blood testing. The age distribution range of subjects was 30-49 years. Weight, height, and body mass index(BMI) were not significantly different between the two groups. Blood pressure was compared, and it was found that the drinker group had mean systolic(SBP) and diastolic blood pressures(DBP) 10mmHg higher than the non-drinker group. Nutrient intake levels of the two groups were not significantly different and were adequate with respect to the recommended dietary allowances. It was found that the drinker group ingested more calories, protein, fat and vitamn B1 than the non-drinker group, while the non-drinker group ingested more carbohydrate, calcium, iron, vitamin A, niacin and ascorbic acid. These differences were believed caused by increased caloric intake from alcohol and additional intake of meat served with drinks for the drinking group. Fourteen of the twenty-five drinkers(56%) had drank regularly for five to ten years. Most drinkers drank 2-3 times per week, with alcohol intake less than two bottles(720ml)of distilled liquor(Soju) at a time. Meat was often served with alcohol as reported by 72% of the drinker group, and was believed to contribute to raised intake of calories, protein and fat in this group. Serum lipid levels of both groups were classified as normal, but the components of total cholesterol, triglycerides were significantly higher in drinkers than non-drinkers. The correlation between triglyceride levels and alcohol intake at one sitting was shown to be significantly positive(r=0.57, p<0.01), so it was believed that triglyceride elevation was associated more with heavy drinking than light drinking. We can conclude that if alcohol is consumed with a normal diet, then serum cholesterol, triglyceride and total lipid levels are expected to increase.

Keywords

References

  1. National Bureau of Statistics Economic Planning Board
  2. Nutr Rev v.45 Moderate alcohol consumption increase plasma high-density lipoprotein cholesterol
  3. Nutrition Update v.1 Nutrition and alcohol. A clinical perspective Shaw S;Lieber CS;Weininger J(ed.);Briggs GM(ed.)
  4. J Nutr v.12 no.2 Role of alcohol abuse in nutritional immunosuppression Watzel B;Watson PR
  5. J Nutr v.91 Fatty liver in the rat after prolonged intake of ethanol with a nutritionally adequate new lipid diet De carli LM;Lieber CS
  6. J Med Prim v.3 An experimental model of alcohol feeding and liver injury in the baboon Liber CS;De Carli LM
  7. Am J Clin Nutr v.33 Alcoholic liver disease; roles of alcohol and malnutrition Mezey E
  8. Brit J Nutr v.54 Influence of chronic ethanol intake on obesity liver statosis and hyperlipidaemia in the Zucker fa / fa rat Karsenty BC;Chanussot F;Ulmer M;Debry G
  9. J Clin Inver v.49 Effect of chronic ethanol feeding on serum lipoprotein metabolism in the rat Baraona E;Liber CS
  10. J Lab Clin Med v.66 no.3 Clinical and experimental mechanism of alcohol-induced hypertriglyceridemia Nestel PJ;Hirsch EZ
  11. Am J Clin Nutr v.33 Effects of alcohol ingestion on lipids and lipoproteins in nomal men: Isocaloric metabolic studies Glueck CJ;Hogg E;Allen C;Garside PS
  12. J Lab Clin Med v.62 no.4 Effect of ethanol on plasma lipidids in man Jones DP;Losowsky MS;Davidson CS;Lieber CS
  13. Korean J Nutr v.22 no.1 Effect of different dietary zinc and protein levels on lipid metabolism Chung MI;Chung YJ
  14. J Korea Soc Food Sci Nutr v.17 no.3 Effect of dietary zinc on the ethanol metabolizing enzyme activity and ethanol elimination rate in rat Jeung JH;Cho SY
  15. European J Clin Inves v.7 Alteractions of lipid metabolism in healthy voluntees during long-term ethanol intake Belfrage P;Berg B;Hagerstrand I;Nilsson-Ehle P;Tornzvist H;Wiebe T
  16. Acta Med Scand Supple v.552 Effects on parameters of liver function, plasma lipid concentrations and lipoprotein patterns Berg B;Johnsson BG
  17. Metabolism v.36 no.6 Effect of moderate alcohol consumption on platelet aggregation Fibrinolsys and blood lipids Pikaar NA;Wedel M;Vander Beek EJ;Van Dokkum W;Kempen HJ;Klufat C;Ockhuizen T;Hermus RJ
  18. Korean J Nutr v.20 no.6 Effect of alcohol consumption and fat content in diet on growth, hepatic function and biochemical indices of blood in rat Choi YS;Chung KH;Lee SH
  19. Korean J Nutr v.27 no.1 A comparative study on serum lipid levels in normals and chronic alcoholics Kim MH;Choi MK
  20. '97 National nutrition survey report Ministry of Health and Welfare
  21. Effect of alcohol intake habits on nutrients intake and weight in adult men Lee SH
  22. Korean J Inter Medi v.29 no.2 A study on liver tissue of chronic alcoholics in korean adult Hong SY;Yang SH;Kim EH
  23. Korean J Epide v.15 no.2 Alcohol intake and coronary heart disease Mang KH
  24. Korean J Community Nutr v.2 no.1 Relation of serum vitamin E and lipoperoxide levels with serum lipid status in korean men Cho SH;Choi YS
  25. J Korean Soc Food Sci Nutr v.25 no.6 A study on drinking, smoking and family disease histories in the family members of cerebrovascular disease patients Choe M;Kim JD;Kim SS
  26. Am J Clin Nutr v.67 Clustering of Cardiovascular disease risk factors among obese school children: The Taipei Children Heart Study Nain-Feng Chu;Eric B Rimm;Dan-Jiang wang;Hsio-Shin Liou;Shyh-Ming Shieh
  27. Am J Clin Nutr v.67 Greater dietary intake of simple carbohydrate is associated with lower concentration of high-density-lipoprotein cholesterol in hypercholesterolemic children Thomas J Starc;Sterven Shea;Lisa C Cohn;Lori Mosca;Welton M Gersony;Richard J Deckelbaum
  28. Am J Clin nutr v.67 Ethanol suppresses smooth muscle cell proliferation in the post prandial state: A new antiatherosclerotic mechanism of ethanol? Rudolf Locher;Paolo M Suter;Wilhelm Vetter