The nuclear medical study on the effect of Hap-Kok(LI4) Acupuncture on cerebral blood flow

합곡(合谷) 침자(鍼刺)가 뇌혈류에 미치는 영향에 대한 핵의학적 고찰

  • Yang Yoo-Sun (Department of the Third medicine, Professional Graduate School of Oriental Medicine, Won-Kwang University) ;
  • Kim Sung-Jin (Department of the Third medicine, Professional Graduate School of Oriental Medicine, Won-Kwang University) ;
  • Hwang Yoo-Jin (Department of the Third medicine, Professional Graduate School of Oriental Medicine, Won-Kwang University) ;
  • Lyu Dong-Soo (Department of the Third medicine, Professional Graduate School of Oriental Medicine, Won-Kwang University) ;
  • Kim Min-Ja (Department of the Third medicine, Professional Graduate School of Oriental Medicine, Won-Kwang University) ;
  • Cho Eun-Hee (Department of Acupuncture & Moxibustion, College of Oriental Medicine, Won-Kwang University) ;
  • Kim Hyun-Jung (Department of Acupuncture & Moxibustion, College of Oriental Medicine, Won-Kwang University) ;
  • Yang Myeong-Bok (Department of Acupuncture & Moxibustion, College of Oriental Medicine, Won-Kwang University) ;
  • Lee Beung-Cheul (Department of Acupuncture & Moxibustion, College of Oriental Medicine, Won-Kwang University) ;
  • Lee In (Department of Circulatory Internal Medicine, College of Oriental Medicine, Won-Kwang University) ;
  • Lee Geon-Mok (Department of the Third medicine, Professional Graduate School of Oriental Medicine, Won-Kwang University)
  • 양유선 (원광대학교 한의학전문대학원 제3의학과) ;
  • 김성진 (원광대학교 한의학전문대학원 제3의학과) ;
  • 황유진 (원광대학교 한의학전문대학원 제3의학과) ;
  • 유동수 (원광대학교 한의학전문대학원 제3의학과) ;
  • 김민자 (원광대학교 한의학전문대학원 제3의학과) ;
  • 조은희 (원광대학교 한의과대학 침구학교실) ;
  • 김현중 (원광대학교 한의과대학 침구학교실) ;
  • 양명복 (원광대학교 한의과대학 침구학교실) ;
  • 이병철 (원광대학교 한의과대학 침구학교실) ;
  • 이인 (원광대학교 한의과대학 순환기내과학실) ;
  • 이건목 (원광대학교 한의학전문대학원 제3의학과)
  • Published : 2001.12.20

Abstract

Objective : To localize and compare the cerebral regions- activated by the the stimulation of traditional and burning acupunctures in right Hap-Kok (LI4) acupoints. Methods : Thirty-four healthy normal volunteers (19 males, 15 females, age 31${\pm}$11 years) were studies by rest/acupuncture Tc-99m HMPAO SPECT using same-dose sequential injection method using right Hap-Kok(LI4), traditional and burning acupunctures. All images were spatially normalized and the differences between rest and acupuncture activation state were statistically analyzed using SPM 96. Results : Statistical analysis of the effect by the stimulation using traditional acupuncture in right L14 showed regional cerebral perfusion increase in right inferior frontal lobe, right straight gyrus, left anterolateral frontal lobe, left anteroinferior temporal lobe, left posterior temporal lobe, and left cerebellum. In the stimulation using burning acupuncture in right LI4, regional cerebral perfusion increased in right posterior prefrontal lobe, right precental gyrus, right postcentral gyrus, right poteroinferior temporal lobe, left precentral gyrus, left Broca's area, left anterior parietal lobe, left posterior prefrontal lobe, and left cerebellum. In right LA, diffuse perfusion increase were noted in the both inferior frontal lobe by traditional acupuncture compared to burning acupuncture. Conclusion : The results localized the cerebral areas showed the effect of the acupuncture on cerebral blood flow. The effects of traditional and burning acupunctures on cerebral blood flow were similar in right Hap-Kok (LI4) acupoints. But the effects of traditional acupunctures on cerebral blood flow are stronger than those of burning acupunctures on cerebral blood flow.

Keywords

References

  1. 鍼灸學(上) 崔容泰(外)
  2. 東醫寶鑑(外形編) 許俊
  3. 대한침구학회지 v.14 no.1 fMRI를 이용한 경혈자극의 대뇌피질 활성변화에 관한 연구법 고찰 Ⅰ 박종배(外)
  4. 경락의 연구Ⅰ 한의학연구소 임상연구부
  5. 경락의 연구Ⅱ 한의학연구소 임상연구부
  6. 경락의 신연구 한의학연구소 임상연구부
  7. Annual Report on the cause of death statistics, 1994 National Statistical Office
  8. 대한침구학회지 v.13 no.1 중풍의 침구치료에 대한 소고 박진웅(外)
  9. Stroke v.25 Perspectives of stroke in persons living in seoul, south korea : A survey of 1000 subjects Kim, J.S.;Yoon, S.S.
  10. Proc. Natl. Acad. Sci. USA v.95 New findings of the correlation between acupoints and corresponding brain cortices using functional MRI Cho, Z.H.;Chung, S.C.;Jones, J.P.;Park, J.B.;Park, H.J.;Lee, H.J.;Wong, E.K.;Min, B.I.
  11. Neuroepidemiology v.12 A randomized controlled trial on the treatment for acute partial ischemic stroke with acupuncture Hu, H.H.;Chung, C.;Liu, T.J.;Chen, R.C.;Chen, C.H.;Chou, P.;Huang, W.S.;Lin, J.C.;Tsuei, J.J.
  12. Chen. Tzu. Yen. Chiu. v.21 Effects of electrical acupuncture on the cerebral blood flow and the pial microcirculatory blood flow in dogs Ji, G.;Zhao, L.;Shi, R.;Liu, Y.;Wang, S.;Wu, F.
  13. Chung Kuo Chung Hsi I Chieh Ho Tsa Chih v.16 Effect of acupuncture on regional cerebral blood flow and cerebral functional activity evaluated with single-photon emission computed tomography Wang, F.;Jia, S.W.
  14. Am. J. Chin. Med. v.23 Non-invasive measurement of brain activity using functional MRI. toward the study of brain response to acupuncture stimulation Yoshida, T.;Tanaka, C.;Umeda, M.;Higuchi, T.;Fukunaga, M.;Naruse, S.
  15. Neurosci. Lett. v.141 Measuring the neuromodulatory effects of drugs in man with positron emission tomography Friston, K.J.;Grasby, P.M.;Bench, C.J.;Frith, C.D.;Cowen, P.J.;Liddle, P.F.;Frackowiak, R.S.; Dolan, R.
  16. Neurosci. Lett. v.13 Brain functional activity during gait in normal subjects: a SPECT study Fukuyama, H.;Ouchi, Y.;Matsuzaki, S.;Nagahama, Y.;Yamauchi, H.;Ogawa, M.;Kimura, J.;Shibasaki, H.
  17. Korean J. Nucl. Med. v.32 Functional brain mapping using H215O positron emission tomography (Ⅰ): Statistical Parametric Mapping Method Lee, D.S.;Lee, J.S.;Kim, K.M.;Chung, J.K.;Lee, M.C.
  18. Korean J. Nucl. Med. v.32 Functional brain mapping using H215O positron emission tomography (Ⅱ): Mapping of human working memory Lee, J.S.;Lee, D.S.;Lee, S.K.;Nam, H.W.;Kim, S.K.;Park, K.S.;Jeong, J.M.;Chung, J.K.;Lee, M.C.
  19. J. Nucl. Med. v.38 SPECT image analysis using statistical parametric mapping: comparison of technetium-99m-HMPAO and technetium-99m-ECD Patterson, J.C.;Early, T.S.;Martin, A.;Walker, M.Z.;Russell, J.M.;Villanueva Meyer H.
  20. 핵의학입문 핵의학교육연구회
  21. 임상중풍학 김영석
  22. Am. J. Chin. Med. v.4 no.2 Acupuncture loci Gunn, G.C.
  23. Am. J. Chin. Med. v.8 no.2 Anatomical findings at acupuncture loci Plummer, J.C.
  24. Acupuncture Research Quarterly v.3 no.2 明堂圖的歷史硏究 Chen, T.H.
  25. 대한침구학회지 v.15 no.2 手陽明大腸經과 관련된 經穴과 顔面神經의 標識領域에 관한 硏究 朴禹順(外)
  26. 火鍼 劉保延
  27. 黃帝內經素問譯解 楊維傑
  28. 대한침구학회지 v.15 no.2 火鍼요법의 연구동향과 DITI를 활용한 임상적 고찰 안수기;박상준
  29. 鍼灸學(상) 전국한의과대학 침구$\cdot$경혈학교실(편저)
  30. 대한침구학회지 v.15 no.2 鍼法에 따른 合谷穴 刺戟이 疼痛抑制에 미치는 影響 윤여충(외)
  31. 東醫臨床指鍼 金庚植
  32. 대한침구학회지 v.16 no.1 合谷穴位鍼刺와 電氣刺戟이 疼痛抑制에 미치는 影響 황병천(外)
  33. Korean J. Nucl. Med. v.33 Change of cerebral blood flow distribution of and vascular reserve according to age in koreans measured by Tc-99m HMPAO brain SPECT Song, H.C.;Bom, H.S.;Sohn, H.K.;Jeong, H.J.;Min, J.J.;Kim, J.Y.(et al.)