YAKHAK HOEJI (약학회지)

The Pharmaceutical Society of Korea (대한약학회)
권호 표지

Inhibitory Effects of Crude Polysaccharide of Water Extract of Art on Melanin Biosynthesis

인진쑥 물추출물의 조다당제에 의한 Melanin 생성억제 효과

  • 천현자 (원광대학교 한의학 전문대학원) ;
  • 안병용 (원광대학교 한의학 전문대학원) ;
  • 한종현 (원광대학교 한의학 전문대학원) ;
  • 우원홍 (원광대학교 한의학 전문대학원)
  • Published : 2001.12.01
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Abstract

Melanogenesis is a physiological process resulting in the synthesis of melanin pigment. We investigated the inhibitory effect of crude polysaccharide of water extract of Artemisia iwayomgi Kitamura (AI) on melanin biosystheies in B16/F10 melanoma cells. Crude polysaccharide of water extract of Artemisia iwayomgi Kitamura significantly inhibited tyrosinase activity and melanin contents with or without $\alpha$-MSH in vivo. Melanin contents and tyrosinase activity were decreased in a dose-dependent manner,These results show that crude polysaccharide of water extract of Artemisia iwayomgi Kitamura could be developed as skin whitening components of cosmetics.

Keywords

References

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