Natural Product Sciences

The Korean Society of Pharmacognosy (한국생약학회)
권호 표지

Antioxidant compounds from the stem bark of Sorbus commixta

  • Na, Min-Kyun (College of Pharmacy, Chungnam National University) ;
  • An, Ren-Bo (College of Pharmacy, Chungnam National University,College of Pharmacy, Yanbian University) ;
  • Lee, Sang-Myung (Korea Research Institute of Bioscience and Biotechnology) ;
  • Min, Byung-Sun (Korea Research Institute of Bioscience and Biotechnology) ;
  • Kim, Young-Ho (College of Pharmacy, Chungnam National University) ;
  • Bae, Ki-Hwan (College of Pharmacy, Chungnam National University) ;
  • Kang, Sam-Sik (Natural Products Research Institute, Seoul National University)
  • Published : 2002.03.01
Download PDF
⟨ Previous Next ⟩

Abstract

The MeOH extract of Sorbus commixta (Rosaceae) exhibited strong DPPH radical scavenging activity, and through activity-guided fractionation two antioxidant compounds were isolated and identified as $catechin-7-O-{\beta}-D-xylopyranoside$ (1) and $catechin-7-O-\;{\beta}-D-apiofuranoside$ (2) by physicochemical and spectrometric methods. To evaluate the antioxidant effect of these compounds, some in vitro tests, such as the DPPH radical scavenging activity test, the superoxide radical scavenging activity test and the lipid peroxidation inhibitory activity test, were performed. Compounds 1 and 2 showed stronger activities than both a-tocopherol and butylated hydroxy anisole (BHA) in each assay.

Keywords

References

  1. Bae, K., The medicinal plants of Korea, Kyo-Hak Publishing, Seoul, 2000, p. 236
  2. Cheng, Z.J., Kuo, S.C., Chan, S.C., Ko, F.N., Teng, C.M., Antioxidant properties of butein isolated from Dalbergiaodorifera. Biochim. Biophysi. Acta. 1392, 291-299 (1998) https://doi.org/10.1016/S0005-2760(98)00043-5
  3. Chiang Su New Medicinal College, Dictionary of Chinese Crude Drugs (Zhong-Yao-Da-Ci-Dian in Chinese), Shanghai Scientificethnologic Publisher, Shanghai, 1977, pp. 1059-1060
  4. Christian, K., Gerhard, M., Peter, A.P, Ein neues catechinglykosid aus Polypodium vulgare. Z. Naturforsch. 37c, 148-151 (1982)
  5. Hiroyuki, R, Tetsuya, S., Nobutoshi, T., Chemical evaluation of Betula species in Japan. 1. Constituents of Betula ermanii. Chem. Pharm. Bull. 43, 1937-1942 (1995) https://doi.org/10.1248/cpb.43.1937
  6. Neuyen, T.T.H., Kinzo, M., Ryoji, K., Kazuo, Y., Hiroshi, W., In vitro antioxidant activity of Vietnamese ginseng saponin and its components. Biol. Pharm. Bull. 21, 978-981 (1998) https://doi.org/10.1248/bpb.21.978
  7. Nishikimi, M., Roa, N.A., Yagi, K., The occurrence of superoxide anion in the reaction of reduced phenazine methosulfate and molecular oxygen. Biochem. Biophysi. Res. Comm. 46, 849-854 (1972) https://doi.org/10.1016/S0006-291X(72)80218-3
  8. Raymond, W.D., Adel, A.M., Sujit, K.C., Structure of the watersoluble feeding stimulant for Scolytus multistriatus: A revisionPhytochemistry. 12, 1153-1155 (1973)
  9. Shengjun, G., Elisabet, F., Lennart, K., Bengt, R., Bo, G.S., Triterpenoid saponins containing an acetylated branched Dfucosyl residue from Quillaja saponariaMolina. Phytochemistry. 53, 861-868 (2000) https://doi.org/10.1016/S0031-9422(99)00422-7
  10. Taco, T., Kitatani, F., Watanabe, N., Yagi, A., Sakata, K., A simple screening method for antioxidants and isolation ofseveral antioxidants produced by marine bacteria from fish and shellfish. Biosci. Biotech. Biochem. 58, 1780-1783 (1994) https://doi.org/10.1271/bbb.58.1780