Korean Journal of Pharmacognosy (생약학회지)

The Korean Society of Pharmacognosy (한국생약학회)
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Phenolic Compounds from Barks of Ulmus macrocarpa and Its Antioxidative Activities

왕느릅나무 수피의 페놀성 화합물 및 항산화 활성

  • Published : 2002.12.30
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Abstract

Phytochemical examination of Barks of Ulmus macrocarpa has led to the isolation and characterization of two fla-vanonol, taxifolin $7-O-{\beta}-D-glucopyranoside$ (1), taxifolin $3'-0-7-{\beta}-glucopyranoside$ (2), two flavanone eriodictyol $7-O-{\beta}-D-glucopyranoside$ (3), nalingenin $7-O-{\beta}-D-glucopyranoside$ (4), three flavan 3-ol, (+)-catechin (5), (-)-epicatechin (6), (+)-catechin 7-O-{\beta}-D-glucopyranoside (7) and one proanthocyanidin, procyanidin B-1 (8). Antioxidative activity of these compounds was determined by measuring the radical scavenging effect on 1,1-diphenyl-2- picrylhydrazyl (DPPH) radicals . (+)-Catechin (5) , (-)-epicatechin (6), (+)-catechin $7-O-{\beta}-D-glucopyranoside$ (7) and procyanidin B-1 (8) showed significant antioxidative activity.

Keywords

References

  1. 정태현(1974) 한국식물 도감,식물편(목,초본류), 106 이문사. 서울
  2. 이영로(1996) 한국 식물 도감, 74: 교학사. 서울
  3. 배기환(2000) 한국의 약용식물, 64: 교학사. 서울
  4. 이경순 외(1998) 중약대사전, 1851: 정담출판사. 서울
  5. Son, B. W., Park, J. H. and Zee, O. P. (1989) Catechin glycoside from Ulmus davidiana. Arch. pharm. Res. 12: 219-222 https://doi.org/10.1007/BF02855558
  6. Kim, S. H., Hwang, K. T. and Park, J. C. (1992) Isolation of flavonoids and determination of rutin from the leaves of Ulmus parvifolia. Kor J. Pharmacogn. 23: 229-234
  7. Moon, Y. H. and Rim, G. R. Studies on the Constituents of Ulmus parvifolia. Kor. J. Pharmcogn. 26: 1-7
  8. Lee, M. K., Sung, S. H., Lee, H. S., Cho, J. H., Kim, Y. C. (2001) Lignan and neolignan glycosides from Ulmus davidiana var. japonica. Arch Pharm Res. 24: 198-201 https://doi.org/10.1007/BF02978256
  9. Kim, J. P., Kim, W. G., Koshino, H., Jung, J., Yoo, I. D., (1996) Sesquiterpene O-naphthoquinones from the root bark of Ulmus davidiana. Phytochemistry. 43: 425-430 https://doi.org/10.1016/0031-9422(96)00279-8
  10. Lee, E. B., Kim, O. K., Jung, C. S. and Jung, K. H. (1995) The influence methanol extract of Ulmus davidiana var. japonica cortex on gastric erosion and Ulcer and Paw Edema in rats. Kor. J. Pharmcol. 39: 671-675
  11. Hong, N. D., Rho, Y. S., Kim, N. J. and Kim, J. S. (1990) A study on efficacy of Ulmi cortex. Kor J. Pharmacogn. 12: 217-222
  12. Yang, Y, Hyun, J. W., Lim, K. H., Kim, H. J., Woo, E. R. and Park, J. (1996) Antineoplastic effect of extracts from traditional medicine plants and various plants (III). Kor. J. Pharmacogn. 27: 105-110
  13. Hatano, T., Edamatsu, R., Hiramatsu, M., Mori, A., Fujita, Y, Yasuhara, T., Yoshida, T. and Okuda, T. (1989) Effects of the interaction of tannins with co-existing substances. . Effects of tannins and ralated polyphenols on superoxide anion radical, and on 1,1-dipheny1-2- picrylhydrazyl radical. Chem. Pharm. Bull, 37: 2016 https://doi.org/10.1248/cpb.37.2016
  14. Haebone, J. B. and Mabry, T. J. (1982) The flavonoids advances in research. Chapman and Hall, London, New York
  15. Agrawal, P. K. (1989) Carbon-13 NMR of flavonoids. Elsevier, New York
  16. Lee, M. W., Tanaka, T, Nonaka, G. and Hahn, D. R. (1992) Phenolic Compounds on the Leaves of Betula platyphylla var. latifolia. Arch. Pharm. Res, 15: 211-214 https://doi.org/10.1007/BF02974056
  17. Lee, Y. A. and Lee, M. W. (1995) Tannins from Rubus coreanum. Kor. J. Pharmadogn., 26: 27-30