Effects of Methanol Extracts from Bamboo(Pseudosasa japonica Makino) Leaves extracts on Lipid Metabolism in Rats Fed High Fat and High Cholesterol Diet

대나무(이대)잎 추출물이 지방 및 고콜레스테롤 식이 급여에 의한 흰쥐의 지방 대사에 미치는 효과

  • Han, Sung-Hee (Dept. of Food Science Wonkwang Health Science College) ;
  • Shin, Mee-Kyung (Dept. of Food of Nutrition, College of Human Environmental Science, Wonkwang University)
  • 한성희 (원광보건대학 식품과학과) ;
  • 신미경 (원광대학교 생활과학대학 식품영양학과)
  • Published : 2002.02.28

Abstract

The effects of Bamboo(Pseudosasa japonica Maki) extracts on serum lipid concentrations were evaluated in rats. Ninety-eight male Sprague-Dawley rats weighing $100{\pm}10g$ were divided into fourty groups and fed high fat diets for four weeks. Experimental groups were administered with following diets; basal fat diet(control), basal and high fat diets with 1% cholesterol and Bamboo(Pseudosasa japonica Maki, -1%, -3%, -5%) extracts. The concentrations of serum triglyceride in rats fed the Bamboo(Pseudosasa japonica Maki) extract, high fat, 1% cholesterol, and Pseudosasa japonica Maki, -1%, -3%, -5% were lower than those in other groups. The concentrations of total cholesterol in the Pseudosasa japonica Maki, -1%, -3%, -5% groups were lower than those in fat diet groups. The concentrations of HDL-cholesterol in serum of the Pseudosasa japonica Maki, -1%, -3%, -5% groups were significantly higer than those of other groups. The levels of LDL-cholesterol in serum of the Pseudosasa japonica Maki, -1%, -3%, -5% groups were tended to be lower than those of other groups. These results suggest that Bamboo(Pseudosasa japonica Maki) extract may reduce elevated levels of serum lipid concentrations in rats fed high fat diets.

흰쥐의 식이섭취량에서 각각 지방 및 고콜레스테롤식이에 대나무 잎 추출물을 병합 급여하지 않는 군에 비하여 대나무잎 추출물 농도를 달리하여 병합 급여한군이 증가하였고, 체중증가량은 각각 지방 및 고콜레스테롤 식이에 대나무잎 추출물을 급여하지 않는 군에 비하여 대나무잎 추출물 농도를 달리하여 병합 급여한군이 감소하였다. 식이효율은 지방식이군에 비하여 대조군이 증가하였으나 유의한 없었다. 또한 각각의 지방식이에 대나무잎 추출물을 급여하지 않는 군에 비하여 대나무 잎 추출물 농도를 달리하여 병합 급여한 군간에는 별다른 차이를 보이지 않았다. 중성지질 농도에서 대조군은 241.17 mg/dL 인데 비하여 지방식이군은 249.00 mg/dL으로 증가하였다. 대나무잎 추출물을 급여하지 않는 각 지방 및 고콜레스테롤 식이군은 $254.00{\sim}255.50\;mg/dL$인데 비하여 대나무잎 추출물을 농도를 달리하여 병합 급여한 군은 $225.60{\sim}240.60\;mg/dL$으로 감소하였으며 특히3% 농도군이 가장 낮았다. 총콜레스테롤 함량에서 대조군은 96.17 mg/dL에 비하여 지방식이군은 124.50 mg/dL으로 유의하게 증가하였다. 대나무 잎 추출물을 급여하지 않는 각각의 지방 및 고콜레스테롤 식이군은 $134.07{\sim}199.33\;mg/dL$인데 비하여 대나무잎 추출물 농도를 달리하여 병함 급여한 군은 $101.13{\sim}131.80\;mg/dL$으로 유의하게 감소하였다. HDL-콜레스테롤 농도에서 대조군은 17.50 mg/dL인데 비하여 지방식이군은 18.50 mg/dL으로 증가하였으며, 각 지방 및 고콜레스테롤 식이군에 대나무 잎 추출물을 병합 급여하지 않는 군은 $16.00{\sim}19.00\;mg/dL$이나 대나무 잎 추출물 농도를 달리하여 병합 급여한 군은$22.00{\sim}24.80\;mg/dL$으로 증가하였다. LDL-cholesterol 함량은 대조군에 비하여 지방 식이군의 함량이 증가하였고, 각각의 지방 및 고콜레스테롤 식이에 대나무잎 추출물 농도를 달리하여 병합 급여한 군은 $92.00{\sim}111.00\;mg/dL$ 인데 비하여 대나무잎 추출물을 급여하지 않는 군은 $111.17{\sim}122.40\;mg/dL$으로 유의적으로 증가하였으며 동맥경화지수는 대나무잎 추출물을 급여시 유의적으로 감소되었다.

Keywords

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