Comparison of biological activities of MeOH extracts in different cultivars and organs of Catharanthus roseus (L.) G.Don

일일초 품종 및 부위별 메탄올 추출물 활성 비교

  • Lee, Hui-Kyoung (Division of Applied Plant Science, College of Agriculture and Life Science, Kangwon National University) ;
  • Kim, Ju-Sung (Division of Applied Plant Science, College of Agriculture and Life Science, Kangwon National University) ;
  • Kim, Myong-Jo (Division of Applied Plant Science, College of Agriculture and Life Science, Kangwon National University) ;
  • Heo, Kwon (Division of Applied Plant Science, College of Agriculture and Life Science, Kangwon National University) ;
  • Lee, Hyeon-Yong (School of Biotechnology and Bioengineering, Kangwon National Uni.) ;
  • Yu, Chang-Yeon (Division of Applied Plant Science, College of Agriculture and Life Science, Kangwon National University)
  • 이희경 (강원대학교 농업생명과학대학 식물응용과학부) ;
  • 김주성 (강원대학교 농업생명과학대학 식물응용과학부) ;
  • 김명조 (강원대학교 농업생명과학대학 식물응용과학부) ;
  • 허권 (강원대학교 농업생명과학대학 식물응용과학부) ;
  • 이현용 (강원대학교 바이오산업공학부) ;
  • 유창연 (강원대학교 농업생명과학대학 식물응용과학부)
  • Published : 2002.09.30

Abstract

Catharanthus roseus was extracted with methanol and its Vinblastine contents and antioxidant and antimicrobial activities in each methanol extracts were determined. Vinblastine contents of leaves were much higher than those in other plant parts. The highest DPPH(1,1-diphenyl-2 -picrylhydrazy) radical scavenging activities in plnat parts showed in leaves of Stardust Orchid and Cooler Rose and the value was $RC_{50}=17\;and\;18\;{\mu}g/ml$ respectively. Leaves of Cooler Rose and Coller Strawberry showed strong antimicrobial activities. Particularly, Cooler Rose showed strong antimicrobial activites except to Penicillium oxalicum.

일일초의 vinblastine 함량과 항산화 및 항미생물의 품종별, 부위별 활성을 조사하였다. vinblastine은 식물체내에 극소량 존재하며 9매품종의 잎에서 대부분 검출이 되었다. 특히 Cooler Coconut의 잎에서의 검출량이 $134.08{\mu}g/ml$로 다른 분획물에 비해 10배 가량 높은 수치를 보였다. 항산화 활성 검증에서는 Stardust Orchid의 잎과 Cooler Rose의 잎의 추출물이 각각 $RC50=17,\;18\;{\mu}g/ml$로 항산화 효과가 높음을 알 수 있었다. 부위별로는 대체적으로 잎, 꽃, 뿌리의 순으로 나타났다. 항미생물 활성 검증에서는 모든 품종의 잎이 꽃보다 높은 활성을 보였으며, 특히 Cooler Rose와 Cooler Strawberry가 활성이 좋게 나타났다. 이상의 시험 결과 항산화 활성이 높은 품종이 항미생물 활성에서도 좋은 결과를 보여주었다. 항산화 활성과 항미생물 활성이 높은 품종을 이용하여 앞으로 이를 이용한 여러 약품이나 식품의 개발이 기대된다.

Keywords

References

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