The Journal of Korean Physical Therapy

The Korean Society of Physical Therapy (대한물리치료학회)
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The Effects of Low Power Laser for the Expression of Epithelial Growth Factor in the Burned Skin of the Rats

흰쥐의 피부화상 후 저강도 레이저 조사가 표피성장인자의 발현에 미치는 영향

  • Lee Sun-Min (Major in Physical Therapy, Dept. of Reabilitation Science, Graduate School, Daegu University) ;
  • Koo Hyun-Mo (Major in Physical Therapy, Dept. of Reabilitation Science, Graduate School, Daegu University) ;
  • Nam Ki-Won (Major in Physical Therapy, Dept. of Reabilitation Science, Graduate School, Daegu University) ;
  • Kim Souk-Boum (Major in Physical Therapy, Dept. of Reabilitation Science, Graduate School, Daegu University) ;
  • Kim Jin-Sang (Department of Physical Therapy, College of Rehabilitation Science, Daegu University)
  • 이선민 (대구대학교 대학원 재활과학과 물리치료학전공) ;
  • 구현모 (대구대학교 대학원 재활과학과 물리치료학전공) ;
  • 남기원 (대구대학교 대학원 재활과학과 물리치료학전공) ;
  • 김석범 (대구대학교 대학원 재활과학과 물리치료학전공) ;
  • 김진상 (대구대학교 물리치료학과)
  • Published : 2002.09.01
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Abstract

This study was performed to investigate the effect of low power laser irradiation on epidermal growth factor(EGF) expression in the burned skin of the rats. Burns of about 3cm in diameter were created with 75'c water on the back of the rats, and the lesion of experimental group were irradiated on days 1, 2, and 3 postwounding. Control tensions were not irradiated. After burns, low power laser irradiation was applied by using 1000Hz, 830nm GaAlAs (Gallium-aluminum- arsenide) semiconductor diode laser. The expression of epidermal growth factor evaluated immunohistochemistry on mouse anti-EGF. The results of this study were as follows 1. In expression of EGF, the lesion of experimental group made EGF to more induce significantly than control tensions. 2. EGF immunoreactivity in burned skin were increased markedly 3 days after burns, and increased gradually from 1 day to 2 days in burns which is laser irradiation These data suggest that low power laser have wound healing effect in the burned skin of the rats.

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