Journal of Korean Medical Science

Korean Acad Medical Sciences (대한의학회)
권호 표지

Epidemiology of Breast Cancer in Korea: Occurrence, High-Risk Groups, and Prevention

Yoo, Keun-Young;Kang, Dae-Hee;Park, Sue-Kyung;Kim, Sook-Un;Shin, Ae-Sun;Yoon, Ha-Chung;Ahn, Se-Hyun;Noh, Dong-Young;Choe, Kuk-Jin

  • Published : 20020200

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Abstract

Breast cancer ranks second or third to uterine cervix cancer and stomach cancer as a cause of death in women, and as a common site of primary cancer. The large difference in its incidence between Westernized and non-Westernized countries is remarkable. There is a linear increase with age that is observed in Western countries, which are high-incidence areas, on the contrary to the inverted V shape curve seen in Asian countries. Epidemiologic studies conducted in Korea have shown that an older age, a family history of breast cancer, early menarche, late menopause, late full-term pregnancy, and never having had a breast-fed child are primary risk factors in the development of breast cancer. The estrogen-augmented-by-progesterone hypothesis explains the roles of these factors to some extent. On the other hand, recent molecular studies have revealed the existence of novel gene environmental interactions. Epidemiological features suggest that the breast cancer incidence rate in Korea will increase, but the age specific curve would not be changed in keeping with what is observed in Western countries. Strategies aimed at controlling breast cancer that include the screening guidelines and the identification of individual predispositions may give us further insights into both the etiology and the prevention of breast cancer.

Keywords

References

  1. Annual report on the cause of death statistics (based on vital registration) National Statistical Office
  2. Yearbook of Health and Welfare Statistics Ministry of Health and Welfare
  3. J Korean Med Sci v.9 Incidence estimation of female breast cancer among Koreans Ahn, Y.O.;Park, B.J.;Yoo, K.Y.;Lee, M.S.;Kim, H.;Noh, D.Y.;Park, J.S.
  4. Annual report of the central cancer registry in Korea (1991. 1-1999. 12). Based on registered data from 128 hospitals Central Cancer Registry Center in Korea
  5. Population-based cancer registry in Seoul, Republic of Korea in 1999 Seoul Cancer registry
  6. Report on cancer registry project from 1992 to 1995 Seoul Cancer Registry Project
  7. Cancer incidence in five continents v.VII Parkin, D.M.;Whelan, S.L.;Ferlay, J.;Raymond, L.;Young, J.(eds.)
  8. 1996 World Health Statistics World Health Organization
  9. Epidemiol Rev v.15 Breast cancer: magnitude of the problem and descriptive epidemiology Kelsey, J.L.;Horn-Ross, P.L.
  10. Breast cancer facts & figures American Cancer Society
  11. Epidemiol Rev v.15 Estrogens, progesterones, normal breast cancer cell proliferation, and breast cancer risk Pike, M.C.;Spicer, D.V.;Dahmoush, L.;Press, M.F.
  12. J Korean Cancer Assoc v.30 High risk group for female breast cancer in Korea Yoo, K.Y.;Park, S.K.;Sung, J.H.;Kang, D.;Kim, Y.C.;Kang, H.S.;Suh, J.S.;Kim, J.S.;Yun, I.J.;Han, S.
  13. Korean J Epidemiol v.17 Epidemiology of breast cancer in Korea Yoo, K.Y.;Noh, D.Y.;Choe, K.J.
  14. J Korean Med Sci v.11 Menstrual and reproductive factors related to the risk of breast cancer in Korea. Ovarian hormone effect on breast cancer Suh, J.S.;Yoo, K.Y.;Kwon, O.J.;Yun, I.J.;Han, S.H.;Noh, D.Y.;Choe, K.J.
  15. Am J Epidemiol v.135 Independent protective effect of lactation against breast cancer: a case-control study in Japan Yoo, K.Y.;Tajima, K.;Kuroishi, T.;Hirose, K.;Yoshida, M.;Miura, S.;Murai, H.
  16. J Korean Cancer Assoc v.25 A case-control study on protective effect of breast feeding against breast cancer among postmenopausal women in Korea Yoo, K.Y.;Noh ,D.Y.;Choe, K.J.
  17. J Korean Surg Soc v.46 Overweight related to the risk of breast cancer by menopausal status in Korea Joo, J.S.;Yoo, K.Y.;Shin, M.H.;Noh, D.Y.;Choe, K.J.
  18. Seoul J Med v.36 Obesity as a determinant of age at menarche and age at menopause in a cross-sectional survey in Yonchon County, Korea Yoo, K.Y.;Bae, J.M.;Park, E.S.;Ha, M.N.;Suh, J.S.;Noh, D.Y.;Choe, K.J.;Park, Y.S.;Lee, H.Y.;Lee, K.S.;Lim, C.Y.;Kim, Y.I.;Shin, Y.S.
  19. Seoul J Med v.33 Trends in mortality and morbidity of uterine cervix, female breast, and ovarian cancer in Korea Yoo, K.Y.;Kim, D.H.
  20. Seoul J Med v.34 Ecological correlation study on nutrients/foods intake and mortality for female breast cancer in Korea Yoo, K.Y.;Kim, D.H.;Shin, M.H.;Noh, D.Y.;Choe, K.J.
  21. Proceedings in the 1st Japan-Russia Medical Exchange Conference Changes in life-style related to female breast cancer in Korea Yoo, K.Y.
  22. Science v.259 Search for a killer: focus shifts from fat to hormones Marshall, E.
  23. J Korean Med Sci v.13 Female sex hormones and body mass in adolescent and postmenopausal Korean women Yoo, K.Y.;Kim H.;Shin, H.R.;Kang, D.;Ha, M.;Park, S.K.;Lee, B.O.;Choe, S.H.
  24. Br J Cancer v.63 Cancers of the prostate and breast among Japanese and white immigrants in Los Angeles County Shimizu, H.;Ross, R.K.;Bernstein, L.;Yatani, R.;Henderson, B.E.;Mack, T.M.
  25. Pharmacogenetics v.10 Alcohol consumption glutathione S-transferase M1 and T1 genetic polymorphisms and breast cancer risk Park, S.K.;Yoo, K.Y.;Lee, S.J.;Kim, S.U.;Ahn, S.H.;Noh, D.Y.;Choe, K.J.;Strickland, P.T.;Hirvonen, A.;Kang, D.
  26. Pharmacogenetics v.11 Relationship between the $Val^{158}Met$ polymorphism of catechol O-methyl transferase and breast cancer Yim, D.S.;Park, S.K.;Yoo, K.Y.;Yoon, K.S.;Chung, H.H.;Kang, H.J.;Ahn, S.H.;Noh, D.Y.;Choe, K.J.;Jang, I.J.;Shin, S.G.;Strickland, P.T.;Hirovonen, A.;Kang, D.
  27. Korean J Epidemiol v.20 Prediction of future breast cancer mortality in Korea Park, S.K.;Lim, Y.K.;Yoo, K.Y.
  28. J Korean Assoc Cancer v.3 High risk group and screening strategy for breast cancer in Korea Yoo, K.Y.;Park, S.K.;Lim, Y.K.