The Korea Journal of Herbology (대한본초학회지)

The Korea Association of Herbology (대한본초학회)
권호 표지

Quantitative Determination of 5-Hydroxymethyl-2-furaldehyde from Rehmanniae Radix Preparata according to Various Processings

熟地黃의 抱製에 따른 5-hydroxymethyl-2-furaldehyde 함량 연구

Lee, Je-Hyeon;Go, Jeong-A;Hwang, Eun-Yeong;Hong, Seon-Pyo
이제현;고정아;황은영;홍선표

  • Published : 20020000

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Abstract

Objectives : Rehmanniae Radix Preparata has been used to enrich blood and supply yin for a several thousand years. We have studied on the quantity of 5-hydroxymethyl-2-furaldehyde (5-HMF) from Rehmanniae Radix Preparata at various processings and tried to develop the making method. Methods : The Rehmanniae Radix Preparata was prepared from the steaming process with rice wine, sterilized rice wine, diluted ethanol and water each other. And the change of 5-HMF was determinated. The analysis of 5-HMF was conducted by HPLC with reversed-phase C18 column and a UV detector at 280 nm. Elution was carried out at 1.0 ml/min with 5% acetonitrile. Results and Conclusions : From this analysis, we found out that the content of 5-HMF was increased with the number of processing times and the content of 5-HMF from Rehmanniae Radix Preparata steamed for 4 times was the same as that of Korea pharmacopoeia.

Keywords

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