The Korea Journal of Herbology (대한본초학회지)

The Korea Association of Herbology (대한본초학회)
권호 표지

Studies on Biological Activity from Extract of Crataegi Fructus

Crataegi Fructus 추출물의 生理活性에 관한 연구

An, Bong-Jeon;Lee, Jin-Tae
안봉전;이진태

  • Published : 20020000

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Abstract

Objectives : This is the study of the application as the ingredients of cosmetics through the examination of the function for physiological activity of Craraegi Fructus, which has been used for herb medicines since ancient times. Method : Korean Craraegi Fructus, which had been extracted, concentrated, and freeze drying with water and ethanol, have been used for the experiment. The effects on elecrtonic donating ability, SOD-like activity, whitening effect, gout and hypertension prevention, Melanoma cell have been researched in the physiological activity measurement of function experiment. Results : According to the physiological activity measurement of function experiment, it have been found that the electronic donating ability has higher effect than BHT, synthetic antioxidant, showing 89.4%~91.8% at 500 ppm. As the concentration increases, the inhibitory effect showed a tendency to rise. However the effect was not so high. Tyrosinase, which is correlated with whitening effect, showed 49.8%~62.4% of the high inhibition ratio at 30,000 ppm. ACE inhibitory effect, which is correlated with hypertension prevention was 32.7%~34.5% at 10ppm but there was no distinctive difference by concentration. According to the result of astringent effect, the ethanol extract from Craregi Fructus showing 89% at 5,000 ppm brought the similar effect to Gerannii Herba and SK_MEL-5, melanoma cell, showed 68.9%~89% of sudden growth inhibition of cell at 50000 ppm, and 10000 ppm. Conclusion : According to the study of the application as cosmetic ingredients, Crataegi Fructus extract has enough merits as a new biological activity ingredient and it will be very effective in the cosmetic industry as the affinitive natural product.

Keywords

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