Pleomorphic Xanthoastrocytoma:Report of 3 Cases

다형성 황색성상세포종 3례

Jo, Jae-Young;Yang, Seung-Min;Min, Byung-Kook;Kwon, Jeong-Taik;Suk, Jong-Sik
조재영;양승민;민병국;권정택;석종식

  • Published : 20020200

Abstract

Pleomorphic xanthoastrocytoma(PXA) is a rare neoplasm with favorable prognosis despite of its aggressive histological features. The authors report three cases of pleomorphic xanthoastrocytomas. The masses were in the temporal or parietal lobe of children or adolscence and presented as complex partial seizures. Total removal of mass was performed in all three cases and the seizure was abscent postoperatively. It is important to differentiate of pleomorphic xanthoastrocytoma from other malignant brain tumors and identify this type of glioma as a distinct entity.

Keywords

References

  1. Cosgrove M, Fitzgibbons PL, Sherrod A, Chandrasoma DT, Martin SE:Intermediate filament expression in astrocytoma neoplasm. Am J Surg Pathol 13:141-145, 1989 https://doi.org/10.1097/00000478-198902000-00007
  2. Kepes JJ:Pleomorphic xanthoastrocytoma:The birth of a dianosis and a concept. Brain Pathol 3:269-274, 1993 https://doi.org/10.1111/j.1750-3639.1993.tb00753.x
  3. Kepes JJ:Xanthomatous lesions of the central nervous system:Definition, classification and some recent observations, in Zimmerman HM(ed):Progress in Neuropathology, New York:Raven Press, 1979, Vol 4, pp196-196
  4. Kepes JJ, Kepes M, Slowik:Fibrous xanthoma and xanthosarcoma of meninges and the brain. Acta Neuropathol(Berl) 23:187-199, 1973 https://doi.org/10.1007/BF00687875
  5. Iwaki T, Fukui M, Kondo A, Matsushima T, Takeshita L:Epithelial properties of pleomorphic xanthoastroytoma determined in ultrastuctural and immunohistochemical studies. Acta Neuropathol(Berl) 74:142-150, 1987 https://doi.org/10.1007/BF00692844
  6. Kepes JJ, Rubinstein LJ, Ansbacher L, Schreiber DJ:Histopathological features of recurrent pleomorphic xanthoastrocytoma:Further corroboration of the glial natures of this neoplasm. A study of three cases. Acta Neuropathol(Berl) 78:585-593, 1989 https://doi.org/10.1007/BF00691285
  7. Kim CH, Choi IS, Bak KH, Kim JM, Oh SJ, Kim NK:Pleomorphic xanthoastrocytoma:Report of three cases. J Korean Neurosurg Soc 28:1008-1014, 1999
  8. Macaulay RJB, Jay V, Hoffman HJ, Becker LE:Increased mitotic activity as a negative prognostic indicator in pleomorphic xanthoastrocytoma. J Neurosurg 79:761-768, 1993 https://doi.org/10.3171/jns.1993.79.5.0761
  9. Pahapil PA, Ramsay DA, Maestro RFD:Pleomorphic xanthoastrocytoma:Case report and analysis of the leterature concerning the efficacy of resection and the significance of necrosis. Neurosurgery 38:822-829, 1996 https://doi.org/10.1227/00006123-199604000-00038
  10. Weldon-Line CM, Victor TA, Groothuis DR, Vick NA:Pleomorphic xanthoastrocytoma:Ultrastructural and immunohistochemical study of a case with a rapidly fatal outcome following surgery. Cancer 52:2055-2063, 1983 https://doi.org/10.1002/1097-0142(19831201)52:11<2055::AID-CNCR2820521115>3.0.CO;2-W