The Korean Journal of Physical Education (한국체육학회지)

Korean Alliance for Health: Physical Education: Recreation:and Dance (한국체육학회)
권호 표지

The effects of Eleutherococcus senticosus extract on human fatigue factors and oxidant - antioxidant system during maximal and submaximal exercise

가시오갈피 투여가 최대부하와 최대하부하 운동시 피로유발요인과 산화-항산화 체계에 미치는 영향

Paik, Il-Young;Park, Tae-Sun;Oh, Se-Wook;Woo, Jin-Hee;Jin, Hwa-Eun;Park, Hyoung-Ran
백일영;박태선;오세욱;우진희;진화은;박형란

  • Published : 20020000
⟨ Previous Next ⟩

Abstract

The purpose of this study is to investigate the effects of Eleutherococcus senticosus supplement on lactate, phosphorous, ammonia, MDA, and GPX during maximal and submaximal exercise. The Subjects in this study were 10 male college students. Ten males were divided into two groups: five Eleutherococcus senticosus supplied (S), five placebo supplied (P) and compared the differences between supplement before(B) and after(A). Obtained results were as follows: In the exercise performance time, S group was increased during submaximal test, and there was significant differences (p<.05). In the blood lactate and phosphorous, SA was higher than SB that was a result of improved exercise performance time by supplying Eleutherococcus senticosus. Whereas in the ammonia, SA was lower than SB that proved an effect of Eleutherococcus senticosus to synthesize energy. In the MDA levels, SA was lower than SB(p<.05), whereas SA was higher than SB in GPX levels(p<.05). In conclusion, it was founded that regular Eleutherococcus senticosus supplement reduce blood lactate, phosphorous, and ammonia accumulation and improve submaximal exercise performance effectively. Also, Eleutherococcus senticosus could inhibit oxidative tissue damage by lipid peroxidation. Therefore, Eleutherococcus senticosus has an effect of pharmacology for clinical treatment, in addition to energy mobilization and fatigue factors reduction, and maintenance of tissue oxidant-antioxidant system horn.

Keywords

References

  1. 백일영. (1996). 인위적 방법에 의한 피로의 연장시 혈중 피로 요인의 변화에 관한 연구. 한국체육학회지. 제35권. 3호.
  2. 백일영, 김정규, 전유섭, 오홍진 (1997). 절대 강도 운동시 혈중 피로 요소의 변화에 의한 피로 기전의 타당성 검증. 한국체육학회지, 제36권 1호.
  3. Asano, K., Takahashi, T., Miyashita, M., Matsuzaka, A., Muramatsu, S., Kuboyama, M., Kugo, H., Imai, J. (1986). Effect of Eleutherococcus senticosus extract on human physical working capacity. Planta Med. ]un;(3):175-7.
  4. Baranov, A. (1982). Medicinal uses of ginseng and related plants in the Soviet Union: recent trends in the Soviet literature. J. Ethnopharmacol. Nov;6(3):339-53.
  5. Bejma, J., Ramires, P., & Ji, L. L. (2000). Free radical generation and oxidative stress with ageing and exercise: differential effects in the myocardium and liver. Acta Physiol. Scand. 169(4):343-351.
  6. Blomstrand, E. E, & Newsholme, E.A. (1996). Glucose-Fatty acid cyde & fatigue involving 5-hydroxytptamine: Maughan, R. J., and Shirreffs, S. M. eds. In:Biochemistry of exercise IX. Human Kinetics Publishers, lnc. ppl85-195.
  7. Blum, J., & Fridovich, I. (1985). Inactivation of glutathione peroxidase by superoxide radical. Archives of Biochemistry and Biophysics. 240:500-508.
  8. Cotran, R. S., Kumar, V., & Collins, Tucker. (1999) Pathologic Basis of Disease. 6th ed. W.B. Saunders Co. Philadelphia. pp494-541.
  9. Demling, R, La Londe, C, Saldinger, P., & Knox, J. (1990). Multiple-organ dysfunction in the surgical patient: Pathophysiology, prevention, and treatment. Curr. Probl. Surg. 30:345-351.
  10. Engelhardt, M, Neumann, G., Berbal, A, & Reuter, L (1998). Creatine supplementation in endurance sports. Med. Sci. Sports Exerc. 30(7):1123-9.
  11. Eschbach, L.F., Webster, M.J., Boyd, J.C., McArthur, P.D, & Evetovich, T.K (2000). The effect of siberian ginseng(Eleutherococcus senticosus) on substrate utilization and performance, Int. J. Sport Nutr. Exerc. Metab. Dec;10(4):444-51.
  12. Febbraio, M. A, & Dancey, J. (1999). Skeletal muscle energy metabolism during prolonged, fatigue exercise. J. Appl. Physiol. 87(6):2341-7.
  13. Fukai, T., Siegfried, M. R, Ushio-Fukai, M, Cheng, Y., Kojda, G., & Harrison, D. G. (2000) Regulation of the vascular extracellular superoxide dismutase by nitric oxide and exercise training. Journal of Clinical Investment. 105(11):1631-1639.
  14. Gaffney, B. T., Hugel, H. M, &Rich, P. A (2001). The effects of Eleutherococcus senticosus and Panax ginseng on steroidal hormone indices of stress and lymphocyte subset numbers in endurance athletes. life Sci. Dec 14;7O(4):431-42.
  15. Gonenc, S., Acikgoz, O., Semin, I., & Ozgonul, H. (2000). The effect of moderate swimming exercise on antioxidant enzymes and lipid peroxidation levels in children. Indian Journal of Physiology and Pharmamlogy. 44(3):340-344.
  16. Guth, H., & Potter, J. D. (1987). Effect of rigor and cycling cross-bridges on the structure of troponin C and Ca2+ affinity of the Ca2+-specific regulatory sites in skeletal rabbit psoas fibers. J. Bioi. Chem: 262:13627-13653.
  17. Hultman, E, & Sahlin, K. (1980). Acid-base balance during exercise. In; Exercise & Sport Sciences Reviews, edited by R. S. Hutton &D. I. Miller. Philadelphia, PA: Franklin Institute. p.41-128
  18. Ji, L. L. (1994). Oxidative stress during exercise: Implication of antioxidant nutrients. Free Radical Biology and Medicine. 18(6):1079-1086.
  19. Lui, J., H. C, Overvik-Douki, E, Hagen, T., Doniger, S. T., Chu, D. W., Brooks, G. A, & Ames, B. N. (2000). Chronically and acutely exercised rats: biomarkers of oxidative stress and endogenous antioxidants. J. Appl. Physiol. 89:21-28.
  20. Metzger, J. M (1992). Perspectives in Exercise Science & Sports Medicine: Mechanism of Chemomechanical Coupling in Sleletal Muscle During Work 1:1-52
  21. Murray, R. M., Granner, D. K, Mayes, P. A, & Rodwell, V. W. (1996). Harper's Biochemistry(Eds). 24th. A Simon & Schuster Company.
  22. Newaz, M. A, & Nawal, N. N. A (1998). Effect of a -Tocopherol on lipid peroxidation and total antioxidant status in spontaneously hypertensive rats. American Journal of Hypertention. 1998(11):1480-1485.
  23. Polidori, M. C, Mecocci, P., Cherubini, A, &Senin, U. (2000). Physical activity and oxidative stress during agnig. Int. J. Sports Med. 21(3):154-157.
  24. Poulsen, H. E., Weimann, A, & Loft, S. (1999). Methods to detect DNA damage by free radicals: relation to exercise. Proc. Nutr. Soc. 58(4):1007-1014.
  25. Pyre, D. B., Smith, J. A, Baker, M.S., Telford, R.D., & Weidemann, M. J. (2000). Neutrophil oxidative activity is differentially affected by exercise intensity and type. J. Sci. Med. Sport. 3(1):44-54.
  26. Rossiter, H. B., Cannell, E. R, & Jakeman, P. M (1996). The effect of oral creatine supplementation on the l000-m performance of competitive rowers. J. Sports. Sci. 14:175-179.
  27. Salminen, A, Kainulainen, H., & Vihko, V. (1984). Endurance training and antioxidants of lung. Experientia. 40:822-823.
  28. Seward, S. W; Seiler, K. S., & Starnes, J. W. (1995). Intrinsic myocardial function and oxidative stress after exhaustive exercise. Journal of Applied Physiology. 79:251-255.
  29. Talbert, L & Pauly, M (1991). Eleutherococcus: King of the Adaptogens. American Institute of Health and Nutrition. pp. 1-16.
  30. Tauler, P., Gimeno, 1., Aguilo, A, Guix, M. P., & Pons, A (1999). Regulation of erythrocyte antioxidant enzytre activities in athletes during competition and short-term recovery. Pflugers Arch. 438(6):782-787.
  31. Vina, J., Gimeno, A, Sastre, J., Desco, C, Asensi, M, Pallardo, F. V., Cuesta, A, Ferrero, J. A, Terada, L. S., Repine, J. E. (2000). Mechanism of free radical production in exhaustive exercise in humans and rats: role of xanthine oxidase and protection by allopurinol. IUBMB Life. 49(6):539-544.
  32. Vincent, H. K, Powers, S. K, Stewart, D. J., Demirel, H. A, Shanely, R. A, & Naito, H. (2000). Short-term exercise training improves diaphragm antioxidant capacity and endurarce, Eur. J. Appl. Physiol. 81(1-2):67-74.
  33. Venditti, P, & Di Meo, S. (1997) Effect of training on antioxidant capacity, tissue damage, and endurance of adult male rats. International Journal of Sports Medicine. Oct;18(7):497-502.