Obstetrics & gynecology science

Korean Society of Obstetrics and Gynecology (대한산부인과학회)
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Prevalence of Osteoporosis of Korean Women based on Bone Mineral Density of the radius and effect of menopause on osteoporosis

한국 여성의 요골 골밀도치에 의한 골다공증의 빈도 및 폐경에 따른 변화

Lee, Hae-Nam;Park, Yong-Mun;Jang, Mi-Kyoung;Byeon, Yong-Jin
이해남;박용문;장미경;변용진

  • Published : 20020700
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Abstract

Objective : To determine the prevalence of osteoporosis based on the measurement of bone mineral density (BMD) and to examine the effect of menopausal status on BMD in Korean women Methods : Ultra-distal and distal radius BMD was measured by dual energy X ray absorptiometry (osteoplan p-DXA) in 296 women. The result was analysed, retrospectively. We diagnosed osteopenia and osteoporosis according to the WHO criteria Results : The ultra-distal and distal radius BMD and T score decreased significantly with increase of age. Of women in their thirties, the prevalence of ultra-distal and distal radial osteoporosis were 0%, 6.2%, and in their forties, they were 7.6%, 3.4% and in their fifties, they were 26.6%, 27.9% and of women in their sixties, they were 81.7%, 87.8%. Of women in their forties and fifties, premenopausal women had a higher BMD result than postmenopausal women in the same age group. Of remenopausal women in their forties, the prevalence of osteoporosis were 4.6%, 2.3% and of postmenopausal women in that age, they were 15.6%, 6.3%. Of premenopausal women in their fifties, the prevalence of osteoporosis were 8.3%, 8.3% and of postmenopausal women in that age, they were 29.9%, 31.3%. Conclusion : With increasing age, the prevalence of osteoporosis increased and the BMD decreased. In the postmenopausal state, this difference became larger.

목적 : 우리나라 여성의 나이에 따른 골밀도의 변화와 골감소증 및 골다공증의 빈도를 알아보고 폐경 전과 후의 골밀도 변화와 골다공증의 빈도를 조사해 골다공증 발생과 폐경과의 관계를 알아보고자 하였다. 연구 방법 : 호르몬 대체요법 및 골대사에 영향을 줄 수 있는 약물복용의 경험이 없는 지방공사 충주의료원을 방문한 여성 296명 (30대 16명, 40대 119명, 50대 79명, 60대 82명)을 대상으로 이중에너지 방사선 흡수 계측기 (osteoplan p-DXA)를 이용하여 요골 말단의 두 부위에서 측정한 골밀도치를 후향적으로 분석하였다. 측정된 골밀도치를 이용하여 WHO의 기준에 따라 골감소증, 골다공증으로 진단하였다. 결과 : 여성의 연령이 증가할수록 요골 말단의 두 부위에서 측정한 골밀도와 T-score는 유의하게 감소하였다. 요골 말단 두 부위에서의 골다공증의 빈도는 30대에서는 0%, 6.2%, 40대에서는 7.6%, 3.4%, 50대에서는 26.6%, 27.9%, 60대에서는 81.7%, 87.8%으로 두 부위 모두에서 연령이 증가함에 따라 증가하였다. 40대와 50대 여성을 폐경 전과 후의 두 군으로 나누어 측정한 골밀도와 T-score는 통계학적으로 유의하지는 않았지만 40대와 50대 여성 모두에게서 폐경 전 군보다 후 군에서 낮았다. 골다공증의 빈도도 40대 폐경 전 군에서는 4.6%, 2.3%였으나 폐경후 군에서는 15.6%, 6.3%로 폐경 후 군에서 높았고 50대에서도 폐경 전 군에서는 8.3%, 8.3%였으나 폐경 후 군에서는 29.9%, 31.3%로 높았다. 결론 : 연령이 증가할수록 골밀도는 낮아지고 골다공증의 빈도는 높아지는데 특히 폐경기 이후에 이러한 변화가 더욱 심해지는 것으로 나타났다.

Keywords

References

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