Maxillofacial Plastic and Reconstructive Surgery

Korean Association of Maxillofacial Plastic and Reconstructive Surgeons (대한악안면성형재건외과학회)
권호 표지

RETROSPECTIVE STUDY ON THE INFLUENCING FACTORS OF SURVIVAL RATE AFTER TREATMENTS OF ORAL CANCER

구강암의 치료 후 생존율에 영향을 주는 인자에 대한 후향적 연구

Cho, Byung-Ho;Min, Seung-Ki;Oh, Seung-Hwan;Lee, Dong-Keun;Kim, Young-Gak
조병호;민승기;오승환;이동근;김용각

  • Published : 20020500
⟨ Previous Next ⟩

Abstract

The objective of this research is to find out the influencing factors to recur oral cancers. The outcomes of 85 patients(male: 62 patients, female: 23 patients) with oral cancer who were not treated any pre-operative radiotherapy, chemotherapy or previous oral surgery, other than routine dento-alveolar procedures and a recent diagnostic biopsy were analysed retrospectively. Actuarial (life tables) survival analysis showed the 5 year survival rate was 58%, 52% for male patients, 72% for female patients. The patients who were under 50 years old showed 71% of 5 year survival rate, 51% of 5 year survival rate were above 51 years old group. Patients who were treated with elective neck dissection showed better prognosis which were shown 73% of 5 year survival rate than not neck dissection which were reveal 45% of 5 year survival rate. In TNM stage of patients, advanced stage showed worse prognosis, but only N stage did not suggest to judge good prognosis. Most patients were treated under postoperative radiation therapy and showed better prognosis.

Keywords

References

  1. Ministry of health and welfare: Assortment of reason for death :209, 2000
  2. Hindle I, Nally F : Oral cancer:A comparative study between 1962 and 1967 and 1980 and 1984 in England and Wales. Br Dent J 170:15, 1991
  3. Lee EW : Early Finding of Oral Cancer and role of dentist: JKDA 24:576-582, 1988
  4. Bastsakis JG: Tumors of Head and Neck, 2nd ed. William& Wilkins:1979, pp 144
  5. Randolph VL, Vallejo A, Spiro RH: Combination therapy of advanced head and neck cancer, Cancer 41:460, 1978
  6. Langdon JD, Harvey PW, Rapidis AD:Oral Cancer. the behaviour and response to treatment of 194 cases. J Maxillofac Surg 5:221, 1977
  7. Worral SF, Corrigan M: An audit of one surgeon's experience of oral squamous cell carcinoma using a computerised malignancy database. Annals of the Royal College of Surgeons of England 77:332, 1995
  8. Helliwell TR, Woolgar JA: Minimum Dataset for Head and Neck Carcinoma Histopathology Reports. Bulletin of the Royal College of Pathologist:354, 1999
  9. Grandi C, Alloisio M, Moglia D: prognostic significance of lymphatic spread in head and neck carcinomas: therapeutic implications. Head Neck Surg 8:67, 1985
  10. O'Brien CJ, Smith JW, Soong SJ: Neck dissection with and without radiotherapy: prognostic factors, patterns of recurrence, and survival. Am J Surg 152:456, 1986
  11. Shons AR, Magallanes F, McQuarrie D: The results of aggressive regional operation in the treatment of cancer of the floor of the mouth. Surg 96: 29, 1984
  12. Frazell EL, Lucas Jr JC: Cancer of the tongue: report of the management of 1554 patients. Cancer 15:1085, 1962
  13. Marchetta FC, Sako K: Results of radical surgery for intraoral carcinoma related to tumor size. Am J Surg 112: 554, 1966
  14. Spiro RH, Strong EW: Epidermoid carcinoma of the mobile tongue: treatment by partial glossectomy alone. Am J Surg 122: 707, 1971
  15. Lam KH: the role of neck dissection in head and neck mucosal squamous cancer. Clin. Bull.:865, 1999
  16. Yuen APW, Wei WI, Wong YM: Elective neck dissection versus observation in the treatment of early oral tongue carcinoma, Head Neck 19: 583, 1997
  17. Kligerman J, Lima RA, Soares JR: Supraomohyoid neck dissection in the treatment of T1/T2 squamous cell carcinoma of oral cavity. Am J Surg 168: 391, 1994
  18. Woolgar JA: Detailed topography of cervical lymph node metastases from oral squamous cell carcinoma. Int J Oral Maxillofac Surg 26:3, 1997
  19. Wollgar JA: T2 carcinoma of the tongue: the histopathologist's perspective. Br J Oral Maxillofac Surg 28:163, 1998
  20. Sobin LH: Wittekind C.(Eds.) Head and neck tumours. In: UICC TNM Classification of Malignant Tumours, 5th Edition. John Wiley & Sons, New York:1997, pp 17-32
  21. Shah JP, Strong E, Spiro PH: Neck dissection: Current status and future possibilities. Clin. Bull.;11:25, 1981
  22. Altman DG: Analysis of survival times. In: Altman DG, editor. Practical Statistics for Medical Research. Chapman and Hall, London 26: 365, 1991
  23. Young JL, Perry Gl, Asire AJ: Canver incidence and motality inthe United States, 1973-1977. SEER-NIH publication No. 81(2330). National Cancer Institute Monograph No. 57, Bethesda, MD, Public Health Service, 1981
  24. Min BI: An investigation of the effect of dental causes in oral cancer. JKDA, 2:112, 1973
  25. Westin T, Jansson A, Zenckert C : Mental depression is associated with malnutrition in patients with head and neck cancer. Arch otolaryngol Head Neck Surg 114: 1449, 1988
  26. Leite : Survival analysis in a sample of oral cancer patients at a reference hospital in Rio de Janeiro. Brazil. Oral Oncology 37:347, 1998
  27. Woolgar JA, Rogers S, West CR: Survival and patterns of recurrence in 200 oral cancer patients treated by radical surgery and neck dissection. Oral Oncology 35:257, 1999
  28. Simon N, James S: The university of washington head and neck cancer measure as a predictor of outcome following primary surgery for oral cancer. Head Neck:394, 1999
  29. Shah JP, Celdon RA: Carcinoma of the oral cavity: Factors affecting treatment failure at primary site and neck. Am J Surg 132:584, 1976
  30. Kalnins IK, Leonard AG: Correction between prognosis and degree of lymph node involvement in carcinoma of the oral cavity, Am J Surg 134:450, 1977
  31. King GD: Trasoral resection for carcinoma of the oral cavity. otolaryngol. Clin. North Am 5:321, 1972
  32. Luiz PK, Rogerio B,: Prognostic significance of the distribution of neck node metastasis from oral carcinoma. Head and Neck:207, 2000
  33. Bocca E, Pignatario O, Parrella F: Treatment of the clinically negative neck in laryngeal cancer patients. Head Neck 18:566, 1996 https://doi.org/10.1002/(SICI)1097-0347(199611/12)18:6<566::AID-HED12>3.0.CO;2-6
  34. Khafif RA, Gelbfish GA, Asase DK: Modified radical neck dissection in cancer of the mouth, pharynx, and larynx, Head Neck 94:942, 1990
  35. Byers RM, EL-Naggar AK, Lee YY: Can We detect or predict the presence of occult nodal metastases in patients with squamous carcinamo of the oral tongue? Head Neck 20:138, 1980
  36. Ho CM, Lam KH, Wei WI: Occult lymph node metastasis in small oral tongue cancers. Head Neck 14: 359, 1992
  37. Wang CC:Cancer of the oral cavity. In: Wang CC, ed. Radiation Therapy for Head and Neck Neoplasms 3rd ed. :1996 pp107-186
  38. Spiro RH, Strong EW: Cancer of the oral cavity, in Suen JY, Myers EN (eds): Cancer of the Head and Neck. New York, NY, Chruchill Livingston:789, 1987
  39. Medina JE, Byers RM: Supraomohyoid neck dssection: Rationale, indications, and surgical technique. Head Neck 11:111, 1989
  40. Lee JG: Detection of residual carcinoma of the oral cavity, oropharynx, hypopharynx, and larynx: A study of surgical margins. Trans Am Acad Ophthalmol Otol 78:49, 1974
  41. Vikram B, Strong EW, Shah JP: Failure in the neck following multimodality treatment for advanced head and neck cancer. Head and Neck cancer. Head Neck Surg 6:724, 1984
  42. Leeman CR, Tiwari RM: The efficacy of comprehensive neck dissection with and without postoperative radiotherapy in nodal metastases of squamous cell carcinoma of the upper respiratory and digestive tracts. Laryngoscope 100: 1194, 1990
  43. Schiff PB, Harrison LB, Strong EW: Impact of the time interval between surgery and postoperaitve radiation therapy on locoregional control in advanced head and neck cancer. J Surg Oncology 43:203, 1990
  44. Zelefsky MJ, Harrison LB: Post operative radiation therapy for squamous cell carcinomas of the oral cavity and oropharynx: impact of therapy on patients with positive surgical margins. International Journal of Radiation, Oncology, Biology and Physic 24:17, 1993