Journal of the Korean Society of Food Science and Nutrition (한국식품영양과학회지)

The Korean Society of Food Science and Nutrition (한국식품영양과학회)
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Effects of Zingiber mioga, Zingiber mioga Root and Zingiber officinale on the Lipid Concentration in Hyperlipidemic Rats

양하, 양하근경 및 생강분말이 고지혈증 유발 흰쥐의 지질성분에 미치는 영향

  • Shin, Jung-Hye (Dept. of Foods and Nutrition, Institute of Agriculture and Life Science, Gyeongsang National University) ;
  • Lee, Soo-Jung (Dept. of Foods and Nutrition, Institute of Agriculture and Life Science, Gyeongsang National University) ;
  • Sung, Nak-Ju (Dept. of Foods and Nutrition, Institute of Agriculture and Life Science, Gyeongsang National University)
  • 신정혜 (경상대학교 식품영양학과, 농업생명과학연구원) ;
  • 이수정 (경상대학교 식품영양학과, 농업생명과학연구원) ;
  • 성낙주 (경상대학교 식품영양학과, 농업생명과학연구원)
  • Published : 2002.08.01
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Abstract

This study was designed to establish the effects of Zingiber mioga, Zingiber mioga root and Zingiber ofiicinale on the lipid concentrations in hyperlipidemic rats. A total of 24 male Sprague-Dawley rats weighing 60$\pm$5g were fed one of four experimental diets for 4 weeks: a control diet (hyperlipidemic diet), diets supplemented with 3% of Z. mioga, 3% Z. mioga roots or 3% Z. officinale. The concentration of total cholesterol in serum was significantly decreased by 31% in Z. mioga group compared to the control group. The HDL-cholesterol concentration was significantly higher in Z. mioga and Z. mioga root supplemented groups than in control group. Triglyceride concentration in serum and liver significantly decreased with 3% Zingiber supplemented groups compared with control group, but had no significant differences among three Zingiber supplemented groups. The contents of total cholesterol triglyceride free cholesterol and cholesteryl ester in liver were remarkably lower in Zingiber supplemented groups than in control group. However, hepatic phospholipid level was not showed significant effect.

고지혈증 유발 식이와 양하, 양하근경 및 생강분말의 혼합급이가 흰쥐의 혈청 및 간장의 지질대사에 미치는 영향을 검토하고자 식이에 각각 3%씩 첨가하여 4주간 실험사육하였다. 혈청 총콜레스테롤 농도는 대조군에 비하여 전 실험군이 유의적으로 낮았으며, HDL-콜레스테롤 농도는 양하와 양하근경 급여군이 대조군에 비하여 높게 나타났다. 유리콜레스테롤 및 콜레스테릴 에스테르의 농도는 전 실험군이 대조군에 비하여 유의적으로 낮았고, 콜레스테릴 에스테르 농도비는 대조군이 72.36%, 실험군에서 62.14~65.33%였다. Chylomicron, LDL 및 VLDL 농도는 대조군에 비하여 전 실험군에서 유의적으로 낮았다. 중성지질 및 인지질은 대조군에 비하여 전 실험군이 유의적으로 낮았다. 간장 중의 총콜레스테롤, 중성지질, 유리콜레스테롤 및 콜레스테릴 에스테르의 농도는 대조군에 비하여 각 실험군에서 유의적인 감소를 나타내었으나 인지질의 농도는 유의적인 차이가 없었다.

Keywords

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