The Korean Journal of Cytopathology (대한세포병리학회지)

The Korean Society for Cytopathology (대한세포병리학회)
권호 표지

Epithelial-Myoepithelial Carcinoma of the Parotid Gland - Report of a Case Misinterpreted as Pleomorphic Adenoma on Fine Needle Aspiration Cytology -

이하선의 상피-근상피암종 - 세침흡인 세포검사에서 다형성선종으로 오진된 1 예 보고 -

  • Kim, Dong-Chul (Department of Clinical Pathology, College of Medicine, The Catholic University of Korea) ;
  • Lee, Kyo-Young (Department of Clinical Pathology, College of Medicine, The Catholic University of Korea) ;
  • Kang, Cang-Suk (Department of Clinical Pathology, College of Medicine, The Catholic University of Korea) ;
  • Shim, Sang-In (Department of Clinical Pathology, College of Medicine, The Catholic University of Korea) ;
  • Lee, Ah-Won (Department of Clinical Pathology, College of Medicine, The Catholic University of Korea)
  • 김동철 (가톨릭대학교 의과대학 임상병리과) ;
  • 이교영 (가톨릭대학교 의과대학 임상병리과) ;
  • 강창석 (가톨릭대학교 의과대학 임상병리과) ;
  • 심상인 (가톨릭대학교 의과대학 임상병리과) ;
  • 이아원 (가톨릭대학교 의과대학 임상병리과)
  • Published : 2002.06.30
Download PDF
⟨ Previous Next ⟩

Abstract

Epithelial-myoepithelial carcinoma(EMC) is a rare, low grade malignant tumor of the salivary glands. The EMC has a distinctive histological appearance comprising ductal structures with an inner epithelial cell component and an outer layer of myoepithelial cells which show plump clear cytoplasm. The cytologic features of the EMC have been rarely described. A correct cytological diagnosis to this rare tumor is difficult with high false negative rate. We report a case of EMC in which fine needle aspiration cytologic findings were misinterpreted as a pleomorphic adenoma.

Keywords

References

  1. Ellis GL, Auclair PL: Atlas of tumor pathology: Tumors of the salivary glands, 3rd ed, Fascicle 17, Washington D.C., AFIP 1996, pp268-281
  2. Kocjan C, Milroy C, Fisher EW, Eveson JW : Cytological features of epithelial-myoepithelial carcinoma of salivary gland : Potential pitfalls in diagnosis. Cytopathology 4:173-180, 1993 https://doi.org/10.1111/j.1365-2303.1993.tb00083.x
  3. Stewart CJR, Hamilton S, Brown IL, Mackenzie K : Salivary epithelial-myoepithelial carcinoma : Report of a case misinterpreted as pleomorphic adenoma on fine needle aspiration(FNA). Cytopathology 8:203-209, 1997
  4. Ng W-K, Choy C, IP P, Shek W-H, Collins RJ : Fine needle aspiration cytology of epithelial-myoepithelial carcinoma of salivary glands : A report of three cases. Acta Cytol 43:675-680, 1999
  5. Stewart CJR, Walker E, Mowat A : Fine needle aspiration cytology of epithelial-myoepithelial carcinoma. Diagn Cytopathol 21:363, 1999
  6. Firat P, Guier G, Sungur A, Akyol U : Fine-needle aspiration biopsy of epithelial-myoepithelial carcinoma. Diagn Cytopathol 24:224-225, 2001
  7. Donath K, Seifert G, Schmitz R : Diagnosis and ultrastructure of the tubular carcinoma of salivary gland ducts. Epithelial-myoepithelial carcinoma of the intercalated ducts. Virchows Arch A Pathol Anat 356:16-31, 1972
  8. Yang GCH, Soslow RA : Epithelial-myoepithelial carcinoma of the parotid : A case of ductal-predominant presentation with cytologic, histologic and ultrastructural correlations. Acta CytoI 43:1113-1118,1999
  9. Wax T, Layfield LJ : Epithelial-myoepithelial cell carcinoma of the parotid gland: A case report and comparison of cytologic features with other stromal, epithelial, and myoepithelial cell containing lesions of the salivary glands. Diagn Cytopathol 14:298-304, 1996
  10. Deere H, Hore J, McDermott N, Levine T : Epithelia1myoepithelial carcinoma of the parotid gland : A case report and review of the cytological and histological features. J Laryngol Otol 115:434-436, 2001
  11. Klijanienko J, Vielh P :Fine-needle sampling of salivary gland lesions VB. Cytology and histology correlation of five cases of epithelial-myoepithelial carcinoma. Diagn Cytopathol 19:405-409, 1998
  12. 남은숙, 강구, 신형식 : 타액션 상피-근상피세포암종의 세포학적 소견 -1예 보고-. 대한세포병리학회지 7:64-68,1996
  13. 권미션, 이승숙, 고재수, 정진행 : 두피에 전이한 상피-근상피암종의 세침흡인 세포학적 소견 -1예 보고-. 대한세포병리학회지 11:93-97, 2000
  14. Arora VK, Misra K, Bhatia A : Cytomorphologic features of the rare epithelial-myoepithelial carcinoma of the intercalated ducts. Virchows Arch A Pathol Anat 356:16-31,1972
  15. Carrillo R, Poblet E, Rocamora A, Rodriguez-Peralto JL : Epithelial-myoepithelial carcinoma of the salivary gland : Fine needle aspiration cytologic findings. Acta Cytol 34:243-247, 1990
  16. Layfield LJ, Glascow B1 : Aspiration cytology of clear-cell lesions of the parotid gland : Morphologic features and differential diagnosis. Diagn Cytopathol 9:705-712, 1993
  17. Orell SR : Diagnostic difficulties in the interpretation of fine needle aspirates of salivary gland lesions : The problem revisited. Cytopathology 6:285-300, 1995