Korean Journal of Pharmacognosy (생약학회지)

The Korean Society of Pharmacognosy (한국생약학회)
권호 표지

Effects of Liriopis Tuber Extracts on Lipid Metabolism in Rats Fed High Cholesterol Diet

맥문동 엑스가 고콜레스테롤 식이를 급여한 횐쥐의 지질대사에 미치는 영향

  • 김은정 (대구가톨릭대학교 약학대학) ;
  • 정성운 (대구가톨릭대학교 약학대학) ;
  • 양준호 (대구가톨릭대학교 약학대학) ;
  • 이인선 (계명대학교 TMR Center) ;
  • 이인자 (대구가톨릭대학교 약학대학)
  • Published : 2003.03.30
Download PDF
⟨ Previous Next ⟩

Abstract

This study was performed to examine the effects of Liriopis Tuber extracts to high cholesterol diet on lipid metabolism in rats. Male Sprague-Dawley rats of $90{\pm}10\;g$ were divided into six groups; basal diet (normal group), 1% high cholesterol diet (control group), high cholesterol diet supplemented with 3%, 5% water extracts (C3W, C5W group) and high cholesterol diet supplemented with 3%, 5% MeOH extracts (C3M, C5M group). These experimental diets were fed for 4 weeks. The lipid contents on serum, liver, feces were lower Lriopis Tuber extracts groups than control group. Especially, the effects of water extract was better than MeOH extract.

Keywords

References

  1. 대한통계협회(1997) 사망원인 통계 연보
  2. Miettinen, T.A. (1987) Dietary fiber and lipids. Am. J. Clin. Nutr. 45: 1237-1242
  3. Kritchevsky, D. (1978) Fiber, lipids and atherosclerosis. Am. J. Clin. Nutr. 31: S65-S74
  4. Koda. A., (1971) Folia Pharmacol. Japan. 67: 223
  5. 김창민 外(1997) 중약대사전. 鼎談出版社 3: 1648-1657
  6. 조성지(1998) 맥문동의 혈당강하 및 항암작용에 관한 연구. 대구가톨릭대학교 석사학위논문
  7. 안지윤(2000) 맥문동의 간 기능 활성에 미치는 영향. 대구가톨릭대학교 석사학위논문
  8. Shibata, M., Noguchi, R., Suzuki, M., Iwase, H., Soeda, K., Niwayama, K., Kataoka, E., Kusuda, K. and Hamano, M. (1971) Pharmacological studies on medicinal plant components 1. On the extracts of ophiopogon and some jolk medicines. Proc. Hoshi. Pharm. 13: 66-76
  9. 백남인(1998) 맥문동 지표성분분리. 경희대학교 대학원
  10. Friedewald, W.T., Levy, R.I., Fredrickson, D.S. (1972) Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin. Chern. 18(6): 499-502
  11. Folch, J., Lees, M. and Sloane-stanley, G.H. (1957) A simple method for the isolation and purification of total lipids from animal tissues. J. Bioi. Chern. 226: 497-509
  12. Dewael, J., Raaymakers, C.E. and Endeman, H.J. (1977) Simplified quantitive determination of total fecal bile acids. Clin. Chim. Acta. 79: 465-470 https://doi.org/10.1016/0009-8981(77)90443-0
  13. Kim, S.O., Rhee, S.J., Rhee, I.K., Joo, G.J. and Ha, H.P. (1998) Effects of dietary xylooligosaccharide on lipid levels of serum in rats fed high cholesterol diet. J. Kor. Soc. Food Sci. Nutr. 27(5): 945-951
  14. Han, E.G., Sung, I.S., Moon, H.G., Cho, S.Y (1998) Effect of codonopsis lanceolata water extract on the levels of lipid in rats fed high fat diet. J. Kor. Soc. Food Sci. Nutr. 27(5): 940-944
  15. Wursch, P. (1979) Influence of tannin-rich Carob Pod fiber on the cholesterol metabolism in the rat. J. Nutr. 109: 685
  16. 이순재, 박흥구(1984) 고지방식이에 따른 휜주의 간장내 지질함량 변화와 병리조직학적 소견. 한국영양학회지. 17:113
  17. Sung, I.S., Kim, M.J. and Cho, S.Y (1997) Effect of quercus acutissima CARRUTHERS extracts on the lipid metabolism. J. Kor. Soc. Food Sci. Nutr. 26(2): 327-333
  18. Hidaka, H., Eida, T., Takijama, T., Tokunaga, T. and Tasluro, Y (1986) Effect of fiuctooligosaccharides on intestinal flora and human health. Bifidobacteria Microflora, 5: 37
  19. Hideo, T. (1994) Health effects of oligosaccharides. Food Technology, 48(10): 61-65
  20. 김성갑(1994) Insulin과 돼지감자 fructo올리고당이 장내 미생물의 생육에 미치는 영향. 서울대학교 석사학위논문
  21. 김성옥(1999) 고콜레스테롤 식이 흰쥐에서 Xylooligo당의 콜레스테롤 대사 및 장기능 개선작용. 대구가톨릭대학교 박사학위논문