The effects of Aurantii Fructus Immaturus and Persicae Semen on an obesity of rats fed high fat diet

枳殼과 桃仁이 高脂肪食餌로 유발된 비만 흰쥐에 미치는 影響

Kim Bong-Hyun;Seo, Bu-Il;Lee Eun-Sook;Kim, Mi-Ryeo;Shin Soon-Shik
김봉현;서부일;이은숙;김미려;신순식

  • Published : 20030000

Abstract

Objectives : We had experiment with Aurantii Fructus Immaturus and Persicae Semen in order to find cure effects for an obesity. Methods : We fed control group rats high fat diet and administered normal saline for 8 weeks. And we fed experimental group rats high fat diet and administered extract of Aurantii Fructus Immaturus and Persicae Semen for 8weeks. Results : The changes of the body weights in Aurantii Fructiis Immaturus group showed a significant decrease at 5, 7 and 8 weeks in comparison with control group. Hut in Persicae Semen group didn't show a significant decrease in comparison with control group. The serum total cholesterol, free fatty acid, lipid, phospholipid level in Aurantii Fructus Immaturus group showed a significant decrease in comparison with control group. The serum level in Persicae Semen group didn't show significant change in comparison with control group. The average size of the epididymal fat cells of the rats in Aurantii Fructus Immaturus group showtd a significant decrease in comparison with control group. but in Persicae Semen group didn't show a significant decrease in comparison with control group. The area '.4 of the fat drops in hepatic lobule of rats in Aurantii Fructus Immaturus and Persicae Semen grou:~ showed a decrease in comparison with control group. but these results were not significant. Conclusion : Results of our research in this paper show that Aurantii Fructus Immaturus might have cure an obesity.

Keywords

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