Clinical Characteristics and Outcome of Hydronephrosis Detected by Prenatal Ultrasonography

Lim, Dae-Jung;Park, Jae-Young;Kim, Jeong-Hyun;Paick, Sung-Hyun;Oh, Seung-June;Choi, Hwang

  • Published : 20031200

Abstract

The widespread use of prenatal ultrasound results in an increased recognition of fetal hydronephrosis. To determine clinical characteristics and postnatal outcome of fetal hydronephrosis, we performed a retrospective study in children diagnosed as having fetal hydronephrosis between 1990 and 2001. 341 children with 427 dilated kidneys were included. Dilatation of the renal pelvis was caused by primary ureteropelvic junction obstruction in 65.6%, multicystic kidney in 9.4%, vesicoureteral reflux in 7.0%, duplex system in 5.4%, ureterovesical junction obstruction in 4.0%, and posterior urethral valves in 3.0%. Hydronephrosis resolved spontaneously in 126 (29.5%) kidneys, with 52.7% of mild hydronephrosis, and 2.6% of severe hydronephrosis. Mean interval to spontaneous resolution was $1.39\;({\pm}1.41,\;SD)$ yr. Surgery was performed in 174 kidneys, including pyeloplasty in 105, ureteroneocystostomy in 23, transurethral incision in 11 and nephrectomy in 9. Most patients had initially high-grade hydronephrosis (p<0.05). Mild hydronephrosis appears to be relatively benign, and in most cases, dilatation improves with time, and thus surgical intervention is not required. On the other hand, moderate or severe hydronephrosis often results in a significantly poor outcome and requires surgical intervention, and therefore, requires closer follow-up both antenatally and postnatally.

Keywords

References

  1. Curr Opin Pediatr v.13 Prenatal hydronephrosis Roth, J.A.;Diamond, D.A.
  2. Br J Urol v.85 Antenatal hydronephrosis: changing concepts in diagnosis and subsequent management Shokeir, A.A.;Nijman, R.J.M.
  3. Ultrasound Obstet Gynecol v.17 Natural history of fetal hydronephrosis diagnosed on mid-trimester ultrasound Sairam, S.;Al-Habib, A.;Sasson, S.;Thilaganathan, B.
  4. J Urol v.161 Vesicoureteral reflux in infants with prenatal hydronephrosis confirmed at birth: racial differences Horowitz, M.;Gershbein, A.B.;Glassberg, K.I.
  5. Pediatr Radiol v.23 Ultrasound grading of hydronephrosis: introduction to the system used by the Society for Fetal Urology Fernbach, S.K.;Maizels, M.;Conway, J.J.
  6. J Urol v.152 no.2 Hydronephrosis by measuring the size of the opposite kidney Koff, S.A.;Peller, P.A.;Young, D.C.;Pollifrone, D.L.
  7. J Urol v.154 Diagnostic criteria for assessing obstruction in the newborn with unilateral hydronephrosis using the renal growthrenal function chart Koff, S.A.;Peller, P.A.
  8. Am J Roentgenol v.166 Distinction between obstructive and nonobstructive hydronephrosis: value of diuresis duplex Doppler sonography Mallek, R.;Bankier, A.A.;Etele-Hainz, A.;Kletter, K.;Mostbeck, G.H.
  9. J Urol v.154 Diuretic enhanced duplex doppler sonography in 33 children presenting with hydronephrosis: A study of test sensitivity, specificity and precision Palmer, J.M.;DiSandro, M.
  10. J Urol v.164 The long-term follow-up of newborns with severe unilateral hydronephrosis initially treated nonoperatively Ulman, I.;Jayanthi, Y.R.;Koff, S.A.
  11. J Urol v.168 Analysis of trends on serial ultrasound for high grade neonatal hydronephrosis Hafez, A.T.;McLorie, G.;Bagli, D.;Khoury, A.
  12. J Urol v.140 Ureteropelvic junction obstruction in the neonate Bernstein, G.T.;Mandell, J.;Lebowitz, R.L.;Bauer, S.B.;Coloclny, A.H.;Retik, A.B.
  13. J Urol v.168 no.4 Optimal timing of initial ultrasonography in newborns with prenatal hydronephrosis Wiener, J.S.;O'Hara, S.M.
  14. J Urol v.157 Renal ultrasonography in newborns with prenatally detected hydronephrosis: why wait? Docimo, S.G.;Silver, R.l.
  15. Urology v.55 Postnatal management of antenatal hydronephrosis using an observational approach Koff, S.A.
  16. Prenat Diagn v.19 Antenatal minimal hydronephrosis: is its follow-up an unnecessary cause of concern? Harding, L.J.;Malone, P.S.;Wellesley, D.G.
  17. J Urol v.144 The postnatal management of hydronephrosis diagnosed by prenatal ultrasound Ransley, P.G.;Dhillon, H.K.;Gordon, I.;Duffy, P.G.;Dillon, M.J.;Barratt, T.M.
  18. J Ultrasound Med v.20 Evaluation and follow-up of fetal hydronephrosis Feldman,D.M.;DeCambre, M.;Kong, E.;Borgida, A.;Jamil, M.;McKenna, P.;Egan, J.F.
  19. J Korean Pediatr Soc v.45 Postnatal outcome of fetal hydronephrosis detected with prenatal ultrasonography Park, Y.J.;Mun, S.J.;Bae, C.W.;Lee, B.H.;Kim, J.I.
  20. J Korean Soc Pediatr Nephrol v.6 Outcome of prenatally diagnosed hydronephrosis: one center experience Kim, Y.H.;Kim, B.J.;Park, M.S.;Pai, K.S.;Yang, J.I.;Kim, H.S.;Kim, P.K
  21. Korean J Urol v.44 Clinical outcome of prenatal hydronephrosis Song, P.H.;Cho, C.K.;Park, T.C.