The Korea Journal of Herbology (대한본초학회지)

The Korea Association of Herbology (대한본초학회)
권호 표지

Effect of Rahmanniae Radix Preparat on the blood components in rats fed on fructose-rich diet

熟地黃이 高果糖사료를 食餌한 쥐의 血液像에 미치는 影響

Cho Eug-Haeng;Kim, Yun-Sang
조응행;김윤상

  • Published : 20030000

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Abstract

Objects : To investigate the effects of Rehmanniae Radix on the blood of rats, the effects of Rehmanniae Radix Preparat(RRP) on serum components was examined. Methods : Test group of male Sprague-Dawley rats was fed a fructose-rich(25 %; w/w) diet for 5 weeks. During the last 2 weeks the animals was orally administrated with the decoction prepared form RRP. Control group of rats was also fed a fructose-rich diet for 5 weeks, but administrated with saline during the last 2 weeks. Normal group was fed a normal diet for 5 weeks, and administrated with saline. And total cholesterol(Tc), triglyceride(TG), glucose, AST and ALT in serum were measured at 5 weeks on the fructose-rich diet. Results and Conclusion : The blood levels of Tc, TG, glucose of control group increased, and the activities of AST and ALT of test group decreased compared with those of normal group. The levels of Tc, TG, glucose of teat group decreased, and the activities of AST and ALT of test group increased compared with those of control group. These results suggested that RRP had some regulatory effects on the levels of blood components.

Keywords

References

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