고혈압환자의 일회성 트레드밀 운동에 따른 혈압과 혈관탄성 반응

이종호

  • Published : 20030000

Abstract

Lee, J.H. Response of acute Treadmill Exercise on Blood Pressure and Vascular Compliance in Essential Hypertension patients. Exercise Science, 12(2): 267-276, 2003. The Propose of this study was to analyze the response of acute treadmill exercise on blood pressure and vascular compliance in essential hypertension patients. Twenty volunteers were studied : hypertension group(10), normal group(10). The experimental group was practicing on a treadmill at HRmax 60% exercise intensity for 30 minutes. We measured blood pressure and vascular compliance on 30minutes pre-exercise and post-exercise. This data were analyzed by dependent t-test and pearson correlation between blood pressure and vascular compliance. The result was as follow: The systolic blood pressure in normal group showed no significant differences between pre-exercise and post-exercise. and diastolic blood pressure in normal group showed no significant differences between pre-exercise and post-exercise. The systolic and diastolic blood pressure in hypertension group showed a significant differences. The vascular compliance measured right and left ankle in normal group and hypertension group which showed significant differences between pre-exercise and post-exercise. The systolic blood pressure in normal group was significantly related with diastolic blood pressure, vascular compliance measured left ankle. And significant relationship was found between vascular compliance measured right and left ankle. However, the diastolic blood pressure wasn't related with vascular compliance measured right and left ankle. The systolic blood pressure in hypertension group was significantly related with diastolic blood pressure, vascular compliance measured right ankle and left ankle. The diastolic blood pressure in hypertension group was significantly related with vascular compliance measured right ankle and left ankle. And significant relationship was found between vascular compliance measured right and left ankle.

이종호. 고혈압환자의 일회성 트레드밀 운동에 따른 혈압과 혈관탄성 반응. 운동과학, 제12권 제2호, 267-276, 2003. 본 연구에서는 본태성 고혈압환자의 일회성 중강도 운동이 운동 후 혈압 강하와 혈관탄성에 미치는 영향을 규명하고, 혈압과 혈관탄성의 관계를 밝히고자 본태성 고혈압환자 10명과 정상인 10명을 대상으로 HRmax 60%의 트레드밀 지속부하 운동을 실시하고 일회성 운동 전․후간 혈압과 혈관탄성을 관찰하였다. 트레드밀운동 실시 전․후 혈압의 차이는 고혈압 집단에서 수축기 혈압과(p<.000), 이완기 혈압(p<.002)에서 유의한 감소를 보였다. 왼발과 오른발의 혈관탄성은 두 집단 모두 유의한 증가를 보였으며, 왼발의 혈관탄성보다 많은 증가를 나타냈다. 고혈압 진단에서 수축기 혈압과 왼발의 혈관탄성(r=.-802), 오른발에서 측정한 혈관탄성(r=-.750)은 유의한 역상관을 보였고, 이완기 혈압과 왼발 혈관탄성(r=-.562), 오른발 혈관탄성(r=-.625) 역시 유의한 역상관을 나타내었다.

Keywords

References

  1. 김성수(1999). 장시간의 유산소성 훈련이 고혈압과 당뇨병을 동반한 비만성인의 혈중 콜레스테롤 농도, 체지방 및 혈압에 미치는 영향. 한국체육학회지. 183~193
  2. 김일곤, 김세훈, 전병화, 전종귀(1998). $\alpha$-, $\beta$-차단제 투여와 지구성 운동이 본태성 고혈압쥐의 혈압과 운동능력에 미치는 효과. 한국운동과학회. 7(1): 53-70
  3. 남상남 외 1인(1997). 음주후 지구성 운동의 적정 강도 모색. 한양대학교 체육과학 연구지. 17호
  4. 전병화, 김일곤, 이재웅, 김세훈, 박진봉, 김국성, 전종귀(2001). 고혈압 백서에서 운동 후 혈압강하 현상. 대한스포츠의학회지, 19(2): 250-259
  5. 남상남, 김일곤(1996). 자연발생 본태성고혈압쥐의 혈압강하를 위한 적정 운동강도 모색. 한양대학교 체육과학연구지
  6. 유승희, 장완성, 이상민, 노호성(2000). 운동형태의 차이가 관상동맥질환자의 운동강도 설정에 미치는 영향. 제38회 한국체육학회 학술발표대회, 575-581
  7. 전종귀, 김일곤, 전병화(1999). 지구성 운동이 자연발생고혈압흰쥐의 대동맥벽 두께, 호르몬 및 혈압에 미치는 효과. 한국운동과학회, 8(2): 135-148
  8. 통계청(1999). 사망원인 순위 보고자료
  9. American College of Sport Medicine.(1995). ACSM's Guidence for Exercise Testing and Prescription. 5th edition: 206
  10. Alan, R., Ehtasham, Q., Mara, B., George, R., Giora, P., & George A.(2001). Peripheral Arterial Responses to Treadmill Exercise Among Healthy Subjects and Atherosclerotic Patients. Circulation., 106: 2084-2089
  11. Arai, Y., J. P. Saul, P. Albrecht, L. H. Hartley, L. S. Lilly, R. J. Cohen, & W. S. Colucci.(1989). Modulation of cardiac autonomic activity during and immediately after exercise. Am. J. Physiol., 256:H132-H141
  12. Chandler M.P. & DiCarlo, S.E.(1998). Acute exercise and genderalter cardiac autonomic tonus differently in hypertensive and normotensive rats. Am. J. Physiol., 274: R510-R516
  13. Chen, Y., M. P. Chandler, & S. E. DiCarlo.(1995). Acute exercise attenuates cardiac autonomic regulation in hypertensive rats. Hypertension, 26: 676-683 https://doi.org/10.1161/01.HYP.26.4.676
  14. Chen, H.I., & Chiang, I.P.(1996) Chronic exercise decreases adrenergic agonist-induced vasoconstriction in spontaneously hypertensive rats. Am. J. Physiol. 271: H977-H983
  15. David, A., Tamara K., Christoph, D., Gatzka, James D., Anthony, M,. Browyn, A.(1999). Muscular Strength Training is Associated with low Arterial Compliance and High Pulse Pressure. Hypertension, 33:1385-1391 https://doi.org/10.1161/01.HYP.33.6.1385
  16. Gibbons, G. H., Pratt, R. E., & Dzau, V. J.(1989). Platelet-derived growth factor isoforms differ in mitogenic effect on adult vascular smooth muscle cells. Circulation
  17. Hagberg, J.M., S.J. Montain, & W.H. Martin, Ⅲ(1989). Effect of exercise training in 60-to 69-year-old persons with essential hypertension Am. J. Cardiol, 64:348-353 https://doi.org/10.1016/0002-9149(89)90533-X
  18. Jacques, Roland, Saliha, Gerard M., & Michel, E.(1998) Aortic Pulse Wave Velocity as a Marker of Cardiovascular Risk in Hypertensive Patients. American Heart Association. Hypertension, 33:1111-1117
  19. John, B., & Warren, I.(1990). The Endothelium : an introduction to current research. NY, Wiley-Liss, Inc: 81-93
  20. Joint National Committee on Detection, Evaluation and Treatment of High Blood Pressure. (1993). The fifth Report of the Joint National Committee on Detection, Evaluation and Treatment of High Blood Pressure(JNC-V). Arch. Intern. Med., 153 : 154-183 https://doi.org/10.1001/archinte.153.2.154
  21. Jonsdottir, I.H., Jungersten, L., Johansson, C., Wennmalm, A., Thoren, P., & Hoffmann P.(1998). Increase in nitric oxide formation after chronic voluntary exercise in spontaneously hypertensive rats. Acta. Physiol. Scand., 162: 149-153 https://doi.org/10.1046/j.1365-201X.1998.0285f.x
  22. Karvonen, M. J., Kentala, E., & Mustala, O.(1957). The effect of training of heart rate : A longitudinal study. annales Medicinae Experimentalis et Biologiae fenniae, 35: 307-315
  23. Kingwell, B.A., Arnold, P.J., Jennings, G.L., & Dart, A.M.(1997). Spontaneous running increases aortic compliance in Wistar-Kyoto rats. Cardiovasc Res., 35: 132-137 https://doi.org/10.1016/S0008-6363(97)00079-5
  24. Kinoshita, A., H. Urata, Y. Tanabe, M. Ikeda, H. Tanaka, M. Shindo, and K. Arakawa.(1988). What types of hypertensives respond better to mild exercise therapy J. Hypertense, 6, Suppl., 4:S631-S633
  25. Klemsdal, T.O., Moan, A., Kjeldsen, S.E.(1999). Effect of selective angiotension II type 1 receptor blockade with losartan on arterial compliance in patient with mild essential hypertension. Blood Press, 8 (4) : 214-9 https://doi.org/10.1080/080370599439599
  26. Margo, J.P., Westerhof, N., Giolma, J.P., Altobelli, SA.(1981). Effect of exercise on aortic input impedance and pressure wave forms in normal humans. Circulation Research., 48: 334-343 https://doi.org/10.1161/01.RES.48.3.334
  27. Shen, W., Zhang, X., Zhao, G., Wolin, M.S., Sessa W., Hintze, T.H.(1994). Nitric oxide production and NO synthase gene expression contribute to vascular regulation during exercise. Med. Sci. Sports Exer., 27(8): 1125-1134