비중격으로부터 기원한 골수외 형질세포종 1예

Hong, Seok-Chan;Lee, Song-Won;Jang, Cheol;Sin, Hyeon-Su
홍석찬;이송원;장철;신현수

  • Published : 20030000

Abstract

The extramedullary plasmacytoma is a neoplastic proliferation of plasmacytes in reticuloendothelial tissues, and it occurs most commonly in the head and neck area, especially in the upper respiratory tract and the oral cavity. The most frequent sites are the paranasal sinuses, nasal cavity and nasopharynx. If histologic diagnosis of plasmacytoma is confirmed, all screening tests are necessary to rule out multiple myeloma. The treatment and prognosis are different according to sites where the extramedullary plasmacytoma is originated. We experienced a case of extramedullary plasmacytoma that originated from the septum in a 60-year-old man. After the embolization, endoscopicgical removal of the mass was carried out. Its histopathologic finging revealed the plasmacytoma of lambda type. Systemic evaluations were done immediately and there was no evidence of systemic involvement. Additional radiotherapy (50 Gy) was performed. After ten months of treatment, there was no evidence of recurrence. So we report this case with a review of the literature

Keywords

References

  1. Shreif JA, Goumas PD, Mastronikolis N, Naxakis SS. Extramedullary plasmacytoma of the nasal cavity. Otolaryngol Head Neck Surg 2001 Jan;124(1):119-20
  2. Hong SC, You YS, Kim ES, Kim SC, Park SH, Kim KJ, et al. Development of KVSS test. Korean J Otolaryngol 1999;42:855-60
  3. Cottle MH. Concepts of nasal physiology as related to corrective nasal surgery. Arch Otolaryngol 1960;72:11-20
  4. Weimert TA, Batsakis JG, Rice DH. Carcionomas of the nasal septum. J Laryngol Otol 1978;92:209-13
  5. Young JR. Malignant tumors of the nasal septum. J Laryngol Otol 1979;93:817-32
  6. Beaty CW, Pearson BW, Kern EB. Carcinoma of the nasal septum: experience with 85 cases. Otolaryngol Head Neck Surg 1982;90:90-4
  7. Hasegawa M, Ishikawa N, Teramura K, Hata Y, Watanabe K, Watanabe I. Surgical approach to tumors arising from the posterior two thirds of the nasal septum. ORL J Otorhinolaryngol Relat Spec 1987;49(3):157-62
  8. Cho SH, Kim HT, Kim MS, Sun DI, Koo Y. A clinical study of malignant neoplasms of the nasal septum. Korean J Otolaryngol 1998;41:68-72
  9. Bertram S. Lymphoreticular disorders. In: Batsakis JG. Tumors of the head and neck, 2$^n^d$ edition The Williams and Wilkins company, Baltimore, 1979. p.471-5
  10. Yoon SK, Suh JS, Park MH, Park YS. A case of extramedullay plasmacytoma of the nasal cavity. Korean J Otolaryngol 1985;41:671-4
  11. Marschalko TV. Uever die sogenannten plasmazelen, ein Beitrag zur Kenntniss der Herkunft der entzundlichen Infiltrationszellen. Arch Dermat 1985;30:241-82
  12. Rha KS, Sung YW, Im DW, Park CI. Extramedullary plasmacytoma of the frontal sinus. Korean J Otolaryngol 1997;40:1026-30
  13. Hong KH, Seo SY, Moon WS. Extramedullary plasmacytoma of the larynx. Korean J Otolaryngol 1997;40:1026-30
  14. Hidaka H, Ikeda K, Oshima T, Ohtani H, Suzuki H, Takasaka T. A case of extramedullary plasmacytoma arising from the nasal septum. J Laryngol Otol 2000 Jan;114(1):53-5
  15. Liebross RH, Ha CS, Cox JD, Weber D, Delasalle K, Alexanian R. Clinical course of solitary extramedullary plasmacytoma. Radiother Oncol 1999 Sep;52(3):245-9
  16. Mayr NA, Wen B-C, Hussey DH, Burns CP, Staples JJ, Doornbos JF, et al. The role of radiation therapy in the treatment of solitary plasmacytomas. Radiother Oncol 1990;17:293-303
  17. Susnerwala SS, Shanks JH, Baneijee SS, Scarife JH, Farrington WT, Slevin NJ. Extramedullary plasmacytoma of the head and neck region: clinicopathological correlation in 25 cases. Br J Cancer 1997; 75:921-7
  18. Wiltshaw E. The natural history of extramedullary plasmacytoma and its relation to solitary myeloma of bone and myelomatosis. Medicine 1976;55:217-38
  19. Holland J, Trenker DA, Wasserman TH, Fineberg B. Plasmacytoma treatment result and conversion to myeloma. Cancer 1992;69:1513-7