Abstract
Purpose: The purpose of this study was to assess the relationship between the result of dacryoscintigraphy and the effect of punctal occlusion in dry eye syndrome. Methods: Dacryoscintigraphy was performed in 86 eyes with dry eye syndrome and collagen plugs were inserted into low punctum. We evaluated the relationship between the results of dacryoscintigraphy and the effect of punctal occlusion with collagen plugs. Results: In 36 eyes, tear transit time was normal in dacryoscintigraphy (Group I). In 28 eyes, tear transit time was more than 20 minutes (Group II). In 18 eyes, no tear transit was seen during 60 minutes and after dripping of normal saline, tear transit was seen (Group III). In 4 eyes, there was no tear transit after dripping of normal saline (Group IV). Symptom reduction after punctal occlusion with collagen plugs was observed in 34 eyes (94%) of Group I and 22 eyes (79%) of Group II . There was no significant differences between the two groups. In Group III, symptom reduction was observed in 4 eyes (22%) and it showed significant differences between the other groups. Conclusions: According to this results, punctal occlusion in dry eye syndrome was not effective in patients who showed tear transit after 60 minutes.
목적 : 건성안 환자의 누점폐쇄효과와 누점폐쇄 전 누도신티그라피 소견과의 상관관계를 알아보고자 하였다. 대상과 방법 : 건성안으로 진단 받은 86안에서 전향적으로 누도신티그라피를 시행하여 눈물의 배출양상을 관찰하고 그 후 collagen plug를 하누점에 삽입하여 증상의 완화정도를 환자에게 판정하도록 하여 상관관계를 알아보았다. 결과 : 누도신티그라피상 동위원소가 정상배출을 보인 경우(Group I)가 36안, 20분이상 지연된 경우(Group II) 28안, 60분 경과후에도 배출되지 않아 생리식염수 점안 후 통과한 경우(Group III) 18안, 생리식염수 점안 후에도 통과하지 않는 경우(Group IV) 4안이었다. Group I 과 II 중 콜라젠 누점폐쇄에 대해 증상호전이 있었던 경우는 각각 34안 (94%), 22안(79%)으로 두 군간에 통계적으로 유의한 차이는 없었다(p>0.05). Group III 대상안 중 증상호전이 있었던 경우는 4안(22%)으로 Group I, II에 비해 통계적으로 유의한 차이가 있었다(p<0.05). 결론 : 건성안 환자에서 누도신티그라피상 60분 경과에도 배출되지 않는 눈물배출이 감소된 환자에서는 콜라젠 누점폐쇄술이 효과적이지 못함을 알 수 있었다.