Infection and chemotherapy

The Korean Society of Infectious Diseases (대한감염학회)
권호 표지

The First Case of Human Brucellosis in Korea

국내 브루셀라균에 감염된 환자 1예

Park, Man-Suck;Woo, Young-Seok;Lee, Min-Jung;Shim, Su-Kyoung;Lee, Hae-Kyung;Choi, Young-Sill;Lee, Woo-Hong;Kim, Ki-Hyun;Park, Mi-Yeoun
박만석;우영석;이민정;심수경;이혜경;최영실;이우홍;김기현;박미연

  • Published : 20031200
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Abstract

Brucellosis is usually transmitted to human by direct contact with Infected animals or by ingestion of unpasteurized dairy products. Because of the wide spectrum of its clinical manifestations, brucellosis may appear as other infections and asymptomatic conditions and, therefore, the diagnosis of the disease is frequently missed or delayed. A 41-years-old livestock worker was attended at a local clinic with headache, undulating fever, fatigue, weight loss presentations but the symptoms were not improved in spite of symptomatic therapy of the disease for 6 weeks. Epidemiological background showed that the patient had often ingested unpasteurized cow milk. We confirmed Brucella abortus infection by STA, ELISA and PCR methods. Symptomatic therapy of the disease with appropriate antibiotics (streptomycin, doxicyclin), had favourable outcome. It´s the first case report of human brucellosis caused by direct contact of brucella infected milk cow or ingestion of raw milk in Korea, since its original identification in 1939.

사육우 중 B. abortus가 감염된 젖소의 생우유를 수 차례 섭취한 과거력이 있었으며, 사육우에 물러 17군데 봉합한 경력이 있는 환자로서 기침, 미열, 식욕부진, 피로감 등 감기 증상으로 자각하고 부근 진료기관에서 치료받았으나 증상이 호전되지 않았다. 혈청학적으로는 STA, ELISA법 및 PCR에 의한 유전자 검출 검사를 통하여 진단하고, 수반된 임상상과 함께 역학적 추적조사 결과를 검토하여 확진하였다. 치료를 위하여 doxycycline, streptomycin 병행 투약하며 경과관찰 결과 증상의 호전을 보였다. 본 임상 증례는 1939년 국내 거주 일본인에서 균 배양검사에 의한 B. abortus 감염이 입증된 이후 첫 사례로 보고하는 바이다.

Keywords

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