The Korean journal of sports medicine (대한스포츠의학회지)

The Korean Society of Sports Medicine (대한스포츠의학회)
권호 표지

Effects of Maximal Graded Exercise Test on the WBC and CRP Levels in Marathon Club Participants

점진적 최대부하 운동이 마라톤 동호인의 WBC와 C-reactive Protein 농도에 미치는 영향

Byun, Jae-Chul
변재철

  • Published : 20030000
⟨ Previous Next ⟩

Abstract

The purpose of this study was to verify the effects of white blood cell and C-reactive protein after the maximal graded exercise test in marathon club participants. None of them has any illness and use of any medication during the experiment. Thirteen healthy male marathon club runners aged between 35-50 years. The experiments group were moderately trained running 36-70 km/week, 3-6 days/week and control group were trained running 12-25 km, 1-2 days/week. The present study showed that V$O_2$max in experiments group was higher than control group but there was no significant differences between group. There was no significant differences on serum total cholesterol, HDL-C and LDL-C levels between groups. There were significant differences on WBC, neutrophil, eosinophil and lymphocyte between before and after maximal graded exercise(p<0.05, p<0.01, respectively). And there was significant differences on plasma C-reactive protein(CRP) level between group(p<0.05). Moreover, plasma CRP level in experiment group was lower than control group(p<0.05). Consequently, the present study has demonstrated that increasing levels of regular physical activity and frequently exercise training may prevent or lower coronary heart disease(CHD) risk by reducing inflammatory markers.

Keywords

References

  1. 최병진. 면역과 운동. 한국사회체육학회지. 4:187-191, 1995.
  2. Levando VA, Suzdal-Nitskii S, Pershin BB, Zykov MP. Study of secretory and antiviral immunity in sportsmen. Sports Training Med Rehab, 1:49-52, 1988.
  3. Moyna NM, Acker GR, Weber KM, Fulton JR, Robertson RJ, Goss FL, Rabin BS. Exerciseinduced alterations in natural killer cell number and function. Eur J Appl Physiol, 74:227-233, 1996.
  4. Nieman DC. Exercise immunology: Practical applications. Int J Sports Med, 18:S91-S100, 1997.
  5. Clakson PM. Antioxidants and physical performance. Crit Rev Food Nutr, 35(12):131-141, 1995.
  6. Alessio HM. Exercise-induced oxidative stress. Med Sci Sports and Exercise, 25(2):218-224, 1993.
  7. McCord, JM. Free radicals and inflammation: Protection of synovial fluid by superoxide dismutase. Science, 185:529-531, 1974.
  8. Liesen H. Dufaux, B, Hollmann, W. Modifications of serum glycoproteins during the days following prolonged physical exercise and influence of physical training. Eur J Appl Physiol, 37:243-254, 1977.
  9. Giuseppe L, Antonella B, Giancesare G, Mario Z. Relation between regular aerobic physical exercise and inflammatory markers. Am J Cardiol, 90:820, 2002.
  10. Mattusch F, Defaux B, Heine O, Mertens I, Rost R. Reduction of the concentration of C- reactive protein following nine months of endu- rance training. Int J Sports Med, 21:21-24, 2000.
  11. Jerome L, Abramson, Vaccarino V. Relationship between physical activity and inflammation among apparently healthy middle-aged and older US adults. Arch Int Med, 162:1286-1292, 2002.
  12. Smith GD, Shipley MJ, Batty GD, Morris JN, Mamot M. Physical activity cause-specific mortality in the whitehall study. Public Health, 114:308-315, 2000.
  13. Sesso HD, Paffenbarger RS, Jr, Lee IM. Physical activity and coronary heart disease in men: The harvard Alumni health study. Circulation, 102:975-980, 2000.
  14. Berlin JA, Colditz GA. A meta-analysis of physical activity in the prevention of coronary heart disease. Am J Epidemiol, 132:612-628, 1990.
  15. Folsom AR, Arnett DK, Hutchinson RG, Liao F, Clegg LX, Cooper LS. Physical activity and incidence of coronary heart disease in middle-aged women and men. Med Sci Sports Exerc, 29:901-909, 1997.
  16. Weissberg PL, Bennett MR. Atherosclerosis an inflammatory disease. N Engl J Med, 340:1928-1929, 1999.
  17. Dufaux B, Order U, Greler H, Hollmann, G. Creactive protein serum concentrations in welltrained athletes. Int J Sports Med, 5:102-106, 1984.
  18. Tisi PV, Hulse M, Chulakadabba A, Gosling P, Shearman CP. Exercise training for intermittent claudication; does it adversely affect biochemical markers of the exercise-induced inflammatory response?. Eur J Vasc En dovasc Surg, 14:344-350, 1997. https://doi.org/10.1016/S1078-5884(97)80283-3
  19. 우진희, 곽이섭. 정기적인 유산소 운동에 따른 WKY, SHR 및 RICO Rat의 심박수, 혈압 및 혈청 지질 성분의 변화 비교. 한국체육학회지, 40 (2):663-670, 2001.
  20. MacKinnon LT. Special feature for the Olympic: Effects of exercise on the immune system: Overtraining effects on immunity andperformance in athletes. Immunol Cell Biol, 78(5):502-509, 2000.
  21. Alessio HM, Blasi ER. Physical activity as a natural antioxidant booster and its effect on a healthy life span. Res Q Exerc Sport, 68:292-302, 1997.
  22. Leeuwenburgh C, Heinecke JW. Oxidative stress and antioxidants in exercise. Curr Med Chem, 8:829-838, 2001.
  23. 황정숙, 이승훈, 박혜순. 한국 성인 남성에서 CRP와 비만과의 관련성. 대한비만학회지, 11(3):303-313, 2002.
  24. 김남익, 윤상호. C-reactive protein(CRP) 농도가 고령자들의 안정시 및 운동부하 검사시 심장혈관계 질환 위험 요소에 미치는 영향. 제40회 한국체육학회 학술발표회, pp629-636 2002.
  25. MacAuley D, McCrum EE, Stott G. Physical activity, physical fitness, blood pressure, and fibrinogen in the northern ireland health and activity survey. J Epidemiol Community Health. 50:258-263, 1996.
  26. Geffken DF, Cushman M, Burke GL, Polak JF, Sakkinen PA, Tracy RP. Association between physical activity and markers of inflammation in a healthy elderly population. Am J Epidemiol, 153:242-250, 2001.
  27. Strachan AF, Noakes TD, Kotzenberg G, Nel AL, Beer FC. C-reactive protein concentrations during long distance running. Br Med J, 289:1247-1251, 1984.