Journal of Oral Medicine and Pain

Korean Academy of Orofacial Pain and Oral Medicine (대한안면통증구강내과학회)
권호 표지

Effect of Vomiting in the Intraoral Incidence of Helicobacter pylori

구토가 Helicobacter pylori의 구강내 발현에 미치는 영향

Kang, Seung-Woo;Yoon, Chang-Lyuk;Ahn, Jong-Mo;Lee, Hyun-Ju;Hur, Woong
강승우;윤창륙;안종모;이현주;허웅

  • Published : 20031200
⟨ Previous Next ⟩

Abstract

구토가 Helicobacter pylori(H. pylori)의 구강내 발현에 있어서 어떤 영향을 미치며, H. pylori의 전염양상과 상관관계가 있는지를 평가하였다. 조선대학교 치과병원 구강내과에 내원한 위․십이지장 질환을 포함한 전신질환의 병력이 없는 환자중에서 한달내 구토 경험이 한번이상 있는 건강한 성인 36명과 대조군으로 구토 경험이 없는 40명을 대상으로 타액내의 H. pylori의 유무 및 검출빈도를 중합효소연쇄반응을 이용하여 분석 평가한 결과 구토 경험이 있는 군에서 30명(83.3%), 그리고 대조군에서 17명(40.2%)이 양성으로 나타나 유의한 차이를 보였다. 이상의 연구결과를 종합하면 구토는 구강내 H. pylori의 발현을 증가시키며 H. pylori의 위장-구강 전염에 중요한 요인임을 알 수 있었고, 구강이 H. pylori의 감염과 전염에 근원이 될 수 있음을 추론할 수 있었다.

Keywords

References

  1. Warren, J.R., Marshall, B.. : Unidentified curved bacilli on gastric epithelium in active chronic gastritis. Lancet. 1 : 1273-1275, 1983
  2. Kazerooni, M., Taollam, M., Ghaderi, A.A.. : Helicobacter pylori seropositivity in patients with hyperemesis gravidarum. Int. J. Gyn. & Obs., 79(3) : 217-220, 2002
  3. Kim, H.C., Kim, J.H., Lee, S.S., et al...: Incidence of Helicobacter pylori detected by PCR and its relation to the potential etiology of recurrent aphthous ulcerations. Kor. J. oral med. 27(4) : 401-413, 2002
  4. Megaraud, F.. : When and how does Helicobacter pylori infection occur?" Gastroenterol. Clin. Biol. 27(3) : 374-379, 2003
  5. Tursi, A., Commarota, G., Papa, A., et al.. : The modes of transmission of Helicobacter pylori infection. Recenti. Prog. Med. 88(5) : 232-236, 1997
  6. Luzza, F., Mancuso, M., Imeneo, M., et al.. : Evidence favouring the gastro-oral route in the transmission of Helicobacter pylori infection in children. Eur. J. Gastroenterol. Hepatol. 12(6) : 623-627, 2000
  7. Leung, W.K., Kris, L.K., Carrie, K.L., et al.. : Isolation of Helicobacter pylori from vomitus in children and its implication in gastro-oral transmission. Am. J. Gastroenterol. 94(10) : 2881-2884, 1999
  8. Cammarota, G., Tursi, A., Mantalto, M., et al.. : Role of dental plaque in the transmission of Helicobacter pylori infection. J. Clin. Gasteroenterol. 22(3) : 174-177, 1996
  9. Li, C., Musich, P.R., Ha, T., et al.. : High prevalence of Helicobacter pylori in saliva demonstrated by a novel PCR assay. J. Clin. Pathol. 48(7) : 662-666, 1995
  10. Madinier, I.M., Fosse, T.M., Minteil, R.A.. : Oral carriage of Helicobacter pylori : a review. J. Periodeontol. 68(1) : 2-6, 1997
  11. Vaira,D., Holton, H., Menegatti, M., et al.. : Routes of transmission of Helicobacter pylori infection. Ital. J. Gastroenterol. Hepatol. 30(3) : 279-285, 1998
  12. Oderda, G.. : Transmission of Helicobacter pylori infection. Can. J. Gastroenterol. 13(7) : 595-579, 1999
  13. Dupont, C., Benhamou, P.H., Kalach, N., Raymond, J.. : Helicobacter Pylori infection in children. Rew. Prat. 50(13) : 1437-1441, 2000
  14. Li, C., Ha, T., Ferguson, D.A., et al.. : A newly developed PCR assay of H. Pylori in gastric biopsy, saliva, and feces. Evidence of high prevalence of H. Pylori in saliva supports oral transmission. Dig. Dis. Sci. 41(11) : 2142-2149, 1996
  15. Dowsett, S.A., Kowolik, M.J.. : Oral Helicobacter Pylori : can we stomach it?. Crit. Rew. Oral Biol. Med. 14(3) : 266-233. 2003
  16. Andersen, R.N., Ganeshkumar, N., Kolenbrander, P.E.. : Helicobacter pylori adheres selectively to Fusobacterium spp. Oral Microbiol. Immunol. 13(1) : 51-54. 1998
  17. Veerman, E.C., Bank, C.M., Namavar, G., et al.. : Sulfated glycans on oral mucin as receptors for Helicobacter pylori. Glycobiology. 7(6) : 737-743, 1997
  18. Pytko-Polonczyk, H., Konturk, S.J., Karczewska, E., Bielanski, W., Kaczmarczyk -Stachowska, A.. : Oral cavity as permanent reservoir of Helicobacter Pylori and Potential source of reinfection. J. Physiol. Pharmacol. 47(1) : 121-129, 1996
  19. Umeda, M., Kobayashi, H., Takeuchi, Y., et al.. : High prevalence of Helicobacter pylori detected PCR in the oral cavity of periodontitis patients. J. Periodontol. 74(1) : 129-134, 2003
  20. Kim, N., Lim, S.H., Lee, K.H., et al.. : Helicobacter Pylori in dental plaque and saliva. Kor. J. Intern. med. 15(3) : 187-194, 2000
  21. Pustorino, R., Nicosia, R., D'Ambra, G., et al.. : The mouth-stomach crossing of Helicobacter pylori. Riv. Eur. Sci. Med. Farmacol. 18(5-6) : 183-186, 1996
  22. Figura, W.. : Mouth-to-mouth resuscitation and Helicobacter pylori infection. Lancet. 1 : 1342-1347, 1996
  23. Parsonnet, J., Shmuely, H., Haggerty. T.. : Fecal and oral shedding of Helicobacter pylori from healthy infected adults. J. Am. Med. Associ. 282(23) : 2240-2245, 1999
  24. Goosen, C., Theron, J., Ntsala, M., et al.. : Evaluation of a novel heminested PCR assay based on the phosphoglucosamine mutase gene for detection of Helicobacter pylori in saliva and dental plaque. J. Clin. Microbiol. 40(1) : 205-209, 2002
  25. Song, Q., Spahr, A., Schmid, R.M., Adler, G., Bode, G.. : Helicobacter pylori in the oral cavity : high prevalence and great DNA diversity. Dig. Dis. Sci. 45(11) : 2162-2167, 2000
  26. Eapen, T., Chuancang, J., David, S.C., Chuanfu, L., Donald, A.F.. : The role of the oral cavity in Helicobacter pylori infection. Am. J. gastroenterol. 92(12) : 2148-2154, 1997
  27. Okuda, K., Adachi, M., Lijima, K.. : The efficacy of antimicrobial mouth rinses in oral health care. Bull. Tokyo Dent. Coll. 39(1) : 7-14, 1998