Korean Journal of Community Nutrition (대한지역사회영양학회지)

The Korean Society of Community Nutrition (대한지역사회영양학회)
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The Effects of Fructose Polymer Levan on the Body Fat Accumulation and Serum Lipid Profiles of Korean Women

레반 Diet 섭취에 의한 한국 여성의 체지방 축적 억제와 혈중 지질의 개선 효과

  • 강순아 (건국대학교 분자생명공학과, 생명분자정보학센터) ;
  • 장기효 (삼척대학교 식품영양학과) ;
  • 이재철 (삼척대학교 식품영양학과) ;
  • 장병일 (㈜리얼바이오텍) ;
  • 임영애 (아주대학교 의과대학) ;
  • 송병춘 (건국대학교 생활과학과)
  • Published : 2003.12.01
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Abstract

This study was performed to investigate the effects of a levan diet on the body fat accumulation and serum lipid composition of 29 Korean women over a period of up to 12 weeks (n=13 for the control group, n=16 for the levan group). The subjects ate an uncooked diet (6 g) with 400$m\ell$ of tap water twice a day. The mean body weight and height measurements of the subjects (levan group) at the outset were 66.0$\pm$8.8kg and 156.7$\pm$5.3cm, respectively. The subjects showed a significant reduction in weight, body fat mass, anthropometric measurements and skinfold thickness during the experimental period. The waist hip ratio (WHR) was 0.88$\pm$0.03 at the outset, and fell to 0.82$\pm$0.05 after 4 weeks. The intake of levan was also influenced on the levels of serum Fe, leptin, lipoprotein lipase, HDL-cholesterol, LDL-cholesterol, and triglyceride. The serum glucose levels were within the normal range during the experimental period. The initial serum triglyceride level was 121mg/dl, but fell to 103mg/dl after 4 weeks of levan supplementation. The current study demonstrates that a levan diet is effective in controlling weight, body fat, HDL-cholesterol, LDL-cholesterol, and triglyceride levels.

Keywords

References

  1. Causey JL, Feirgat JM, Gallaher DD, Tungland BC, Slavin JL (2000): Effects of dietary inulin on serum lipids, blood glucose and the gastrointestinal environment in hypercholesterolemic men. Nutr Res 20(2): 191-200
  2. Colker MC, Kalman DS, Torima GC, Pedis T, Street C (1999): Effects of citrus aurantium extract, caffeine, and St. John's wrot on body fat loss, lipid levels, and mood states in overweight healthy adults, Current Therapeutic Res 60: 145-153
  3. Considine RV, Sinha MK, Heiman ML, Kriauciunas A, Stephens TW, Nyce MR, Ohannesian JP, Marco CC, Mckee U, Bauer TL, Caro JF (1996): Serum immunoreactive-leptin concentrations in normalweight and obese humans, New Eng J Med 334 (5): 292-295
  4. Cruz ML, Williamson DH (1992): Refeeding meal-fed rats increase lipoprotein lipase activity and deposition of dietary $[^{14}C]$ lipid in white adipose tissue and decrease oxidation to $^{14}CO_2$. Biochem J 285: 773-778
  5. Daubioul CA, Taper HS, Wispelaere LD, Delzenne NM (2000): Dietary oligo-fructose lessens hepatic steatosis, but does not prevent hypertriglyceidemia in obese Zucer rats. J Nutr 130: 1314-1319
  6. Delzenne NM, Kok NN (1999): Biochemical basis of oligofructose-induced hypolipidemia in animal models, J Nutr 129(7 suppl): 1467s-1470s
  7. Deshaies Y, Begin F, Savoie L, Vachon C (1990): Attenuation of mealinduced increase in plasma lipids and adipose tissue lipoprotein lipase by guar-gum in rats. J Nutr 120: 64-70
  8. Guerre-Millo M (1997) : Regulation of ob gene and overexpression in obesity, Biomed & Pharmacother 51 : 318-323
  9. Ha TY, Kim NY (2003): The effects of uncooked grains and vegetables with mainly brown rice on weight control and serum components in Korean overweight/obese female. Kor J Nutr 36 (2): 183-190
  10. Han YW (1990): Microbial levan. Adv Appl Microbiol 35: 171-194
  11. Havel PJ (2000): Role of adipose tissue in body-weight regulation: mechanisms regulating leptin production and energy balance. Proc Nutr Soc 59(3): 359-371
  12. Havel PJ, Kasim KS, Mueller W, Johnson PR, Gingerich RL, Stem JS (1996) : Relationship of plasma leptin to plasma insulin and adiposity in normal weight and overweight women: effects of dietary fat content and sustained weight loss. J Clin Endo Met 81 (I2) : 4406-4413
  13. Jackson KG, Taylor GR, Clohessy AM, Willians CM (1999): The effect of the daily intake of inulin on fasting lipid, insulin and glucose concentration in middle-aged men and women. Br J Nutr 82(1): 23-30
  14. Jang KH, Kang SA, Cho Y, Kim YY, Lee YJ, Hong K, Jang EK, Kim CH, Choue R (2003): The effects of levan and inulin on the growth of lactic acid-producing bacteria and intestinal conditions in rats. Kor J Nutr 35 (9): 912-918
  15. Kang SA, Hong KH, Jang KH, Kim SH, Jang EK, Kim CH, Choue R (2002): Effects of low level of levan feeding on serum lipids, adiposity and UCP expression in rats. J Korean Soc Food Sci Nutr 31 (5) : 788-795
  16. Kang SA, Hong KH, Kim SH, Jang KH, Kim CH, Choue R (2003): Effects of dietary levan on adiposity, serum leptin and UCP expression in obese rats fed high fat diet. Kor J Nutr 35 (9): 903-911
  17. Kang SA, Jang KH (2003): Research and market trends in levan. Food Sci and Ind 36 (2): 85-91
  18. Katai K (1942) : Trace components in mulberry leaves. J Chem Soc Jpn 18: 379-383
  19. Kim JH, Wang SG (1997): Effects of mugwort, dried orange peel and duchung on lipid metabolism in hyperlipidemia rats. Kor J Nutr 30: 895-903
  20. Kim SK, Kim SY, Kim HJ, Kim AJ (2001): The effect of mulberry leaf extract on the body fat accumulation in obese fa/fa male zucker rats. J Korean Soc Food Sci Nutr 30: 516-520
  21. Kok NN, Roverfroid M, Delzenne N (1996): Dietary oligofructose modifies the impact of fructose on hepatic triacylglycerol metabolism. Metabolism 45 (12): 1547-1550
  22. Kok NN, Taper HS, Delzenne NM (1998): Oligofructose modulates lipid metabolism alterations induced -by a fat-rich in rats. J Appl Tosicol 18(1): 47-53
  23. Kondo Y (1957): Trace constituents of mulberry leaves. Nippon Sanshigaku Zasshi 26: 349-353
  24. Krotriewski M (1983): Impact of obesity on metabolism in men and women: Importance of regional adipose tissue distribution. J Clin Invest 72: 1150-1162
  25. Lee HY (1997): A study on effects of aloe added diet control program S-28 on obese women. J Korean Soc Study Obesity 6: 75-84
  26. Lee SH, Cho JM, Lee MS, Cho BN, Jew SS, Cho YH, Kim KT, Jin DK, Rho SN (2003): The effects of programmed dietary system of a mixture of natural supplements on the composition, serum lipids and the leptin levels. Kor J omm Nutr 8: 356-367
  27. Loo JV, Cummings J, Delzenne N, Englyst D, Quigley M, Roberfroid M, van Vliet T, van den Heuve IE (1999): Functional food properties of non-digestible oligosaccharides: a consensus report from the ENDO project (DGXII AIRII-CT94-1095). Br J Nutr 81: 121-132
  28. Moon HN, Hong SJ, Suh SJ (1992): The prevalence of obesity in children and adolescents. Kor J Nutr 25: 413-418
  29. Ohlson LD, Stuardsudd Lk (1985): The influence of body fat distribution on the incidence of diabetes mellitus. Diabetes 34: 1055-1058
  30. Rhee SK, Song KB, Kim CH, Park BS, Jang EK, Jang KH (2002): Biopolymers. Vol. 5. Polysaccharides L 'Levan'. pp 351-377 WileyVCH Verlag Gmbh. Germany
  31. Son HH, Park MR, Rhee SJ (2002): Effects of dietary xylooligosaccharides on lipoprotein lipase activity in epididymal adipose tissue and lipid composition in serum of rats fed high fat diets. Kor J Nutr 35 (10): 1023-1030