Archives of Pharmacal Research

The Pharmaceutical Society of Korea (대한약학회)
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Antibacterial Compounds from the Leaves of Acanthopanax senticosus

  • Lee, Sang-Hyun (Natural Products Research Institute and College of Pharmacy, Seoul National University) ;
  • Shin, Dong-Sun (Natural Products Research Institute and College of Pharmacy, Seoul National University) ;
  • Oh, Ki-Bong (Natural Products Research Institute and College of Pharmacy, Seoul National University, Graduate School of Agricultural Biotechnology, Seoul National University) ;
  • Shin, Kuk-Hyun (Natural Products Research Institute and College of Pharmacy, Seoul National University, Seokwon Life Science Research Institute)
  • Published : 2003.01.01
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Abstract

Chiisanogenin (1), hyperin (2) and chiisanoside (3) were isolated from the leaves of Acanthopanax senticosus, and were tested for their inhibitory activities against 6 strains of bacteria. Among them, chiisanogenin (1) revealed broad but moderate antibacterial activities against G(+) and G(-) bacteria, the minimum inhibitory concentration (MIC) being in the range of 50-100 $\mu\textrm{g}$/ml.

Keywords

References

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