Journal of the Korean Wood Science and Technology
- Volume 31 Issue 5
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- Pages.88-95
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- 2003
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- 1017-0715(pISSN)
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- 2233-7180(eISSN)
Alkaloids from fruits of Piper nigrum
후추(Piper nigrum) 열매의 Alkaloids
- Park, Il-Kwon (Div. Forest Insect Pests and Disease, Korea Forest Research Institute) ;
- Lee, Hak-Ju (Div. Wood Chemistry & Microbiology, Korea Forest Research Institute) ;
- Lee, Sang-Gil (Div. Forest Insect Pests and Disease, Korea Forest Research Institute) ;
- Shin, Sang-Chul (Div. Forest Insect Pests and Disease, Korea Forest Research Institute) ;
- Park, Ji Doo (Div. Forest Insect Pests and Disease, Korea Forest Research Institute) ;
- Choi, Don-Ha (Div. Wood Chemistry & Microbiology, Korea Forest Research Institute) ;
- Ahn, Young-Joon (Div. Applied Biology and Chemistry, College of Agriculture and Life Sciences, Seoul Nation University)
- 박일권 (임업연구원 산림병해충과) ;
- 이학주 (임업연구원 화학미생물과) ;
- 이상길 (임업연구원 산림병해충과) ;
- 신상철 (임업연구원 산림병해충과) ;
- 박지두 (임업연구원 산림병해충과) ;
- 최돈하 (임업연구원 화학미생물과) ;
- 안용준 (서울대학교 응용생물화학부)
- Received : 2003.01.24
- Accepted : 2003.08.03
- Published : 2003.10.26
Abstract
Five amide alkaloids were isolated from the fruits of Piper nigrum. The structures were determined as : pellitorin (I), quineensine (II), pipercide (III), retrofractamide A (IV), and piperine (V) respectively on the basis of spectrosopic data.
후추 열매의 MeOH 추출물로부터 silica gel 및 preparative HPLC 칼럼 크로마토그라피를 이용하여 5종의 알카로이드 화합물을 단리하였으며, NMR, MS 등의 기기분석 결과, N-isobutyl amide alkaloids인 pellitorin (I)를 비롯하여, quineensine (II), pipercide (III), retrofractamide A (IV)과 piperidine alkaloid인 piperine (V)으로 각각 동정하였다.